18643-84-0Relevant academic research and scientific papers
PREPARATION OF TRANS,TRANS MUCONIC ACID AND TRANS,TRANS MUCONATES
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Page/Page column 30-31, (2010/12/29)
The present invention relates to the isomerization of cis,cis and/or cis,trans muconic acid or esters thereof to trans,trans muconic acid or esters thereof and to the esterification of such muconic acids.
PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING
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Page/Page column 119-120, (2009/11/29)
The invention provides novel inhibitors of hedgehog signaling that are useful as s therapeutic agent for treating malignancies where the compounds have the general formula (I): where A, X, Y R1, R2, R3, R4, m and n are as described herein.
Pyridyl inhibitors of hedgehog signalling
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Page/Page column 88-89, (2010/10/20)
The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I: wherein A, X, Y R1, R2, R3, R4, m and n are as described herein.
Process and intermediates for the preparation of halogenated protease inhibitors
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, (2008/06/13)
This invention relates to novel intermediate compounds which are useful for producing the halogenated protease inhibitors that are the subject matter of U.S. Pat. No. 4,469,885. In particular, the invention relates to novel methods and intermediates for making said protease inhibitors, the intermediate compounds being of the formula: STR1 wherein R1 is: (a) straight or branched chain lower alkyl having 1-6 carbon atoms; or (b) H; wherein R6 is: (a) straight or branched chain higher alkyl having 13-25 carbon atoms; or (b) straight or branched chain higher alkenyl having 13-25 carbon atoms; wherein R5 is: (a) straight or branched chain lower alkyl having 1-6 carbon atoms; or (b) benzyl; wherein R7 is: (a) straight or branched chain lower alkyl having 1-6 carbon atoms; or (b) H; wherein R2 is: (a) --Cl, --Br, or --I; or (b) --CF3.
