431981-80-5

Upstream product

• 431981-78-1 p-methoxyphenyl 3-O-allyl-2,4,6-tri-O-benzoyl-α-D-mannopyranoside 
• 319922-17-3 p-methoxyphenyl 3-O-allyl-α-D-mannopyranoside 
• 28541-75-5 p-methoxyphenyl α-D-mannopyranoside 
• 545-06-2 trichloroacetonitrile 
• 431981-79-2 3-O-allyl-2,4,6-tri-O-benzoyl-α-D-mannopyranose 

Downstream Products

• 431981-84-9 methyl 3-O-allyl-2,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1->3)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside 
• 863914-94-7 benzyl 2-O-[(3-O-allyl-2,4,6-tri-O-benzoyl-α-D-mannopyranosyl)-(1->3)-(2,4,6-tri-O-benzoyl-α-D-mannopyranosyl)]-3,4,6-tri-O-benzyl-α-D-mannopyranoside 
• 863914-96-9 benzyl 2-O-[(3-O-allyl-2,4,6-tri-O-benzoyl-α-D-mannopyranosyl)-(1->3)-(2,4,6-tri-O-benzoyl-α-D-mannopyranosyl)-(1->3)-(2,4,6-tri-O-benzoyl-α-Dmannopyranosyl)]-3,4,6-tri-O-benzyl-α-D-mannopyranoside 
• 863914-92-5 benzyl 2-O-(3-O-allyl-2,4,6-tri-O-benzoyl-α-D-mannopyranosyl)-3,4,6-tri-O-benzyl-α-D-mannopyranoside 
• 1144492-28-3 benzyl 3-O-allyl-2,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1-3)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside 
• 1189322-87-9 C₆₄H₅₆O₁₇ 
• 500217-14-1 3-O-allyl-2,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1-3)-2,4,6-tri-O-benzoyl-α-D-mannopyranosyl trichloroacetimidate 
• 500217-12-9 p-methoxyphenyl 2,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1-3)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside 
• 500217-13-0 C₅₇H₅₀O₁₇ 
• 431981-85-0 methyl 2,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1->3)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside 
• 500217-11-8 p-methoxyphenyl 3-O-allyl-2,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1-3)-2,4,6-tri-O-benzoyl-α-D-mannopyranoside 

Relevant academic research and scientific papers

An improved synthetic route to the potent angiogenesis inhibitor benzyl manα(1→3)-Manα(1→3)-Manα(1→3) -Manα(1→2)-Man Hexadecasulfate

An improved synthetic route to α(1→3)/α(1→2)-linked mannooligosaccharides has been developed and applied to a more efficient preparation of the potent anti-angiogenic sulfated pentasaccharide, benzyl Manα(1→3)-Manα(1→3)-Manα(1→3) -Manα(1→2)-Man hexadecasu

An efficient and practical synthesis of α-(1→3)-linked mannohexaose and mannooctaose

α-(1→3)-Linked mannohexaose and mannooctaose as their methyl glycosides were synthesized from condensation of the corresponding α-(1→3)-linked di- (9) and tetrasaccharide donor (21) with the tetrasaccharide acceptor (23), respectively, followed by deacylation. The donor 21 and acceptor 23 were prepared readily from activation of C-1 of the tetrasaccharide 20 and deallylation of the tetrasaccharide 22, respectively. The tetrasaccharide 20 was prepared from oxidative cleavage of 1-O-p-methoxyphenyl of 19, which was obtained from coupling of 9 with 11. The tetrasaccharide 22 was obtained from condensation of the donor 13 with the acceptor 18. These disaccharides 9, 11, 13, and 18 were produced easily by simple chemical transformation using p-methoxyphenyl 3-O-allyl-α-D-mannopyranoside (1) and 2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl trichloroacetimidate (6), and methyl 3-O-allyl-α-D-mannopyranoside (14) as the synthons.