863914-96-9

Upstream product

• 863914-95-8 benzyl 2-O-[(2,4,6-tri-O-benzoyl-α-D-mannopyranosyl)-(1->3)-(2,4,6-tri-O-benzoyl-α-D-mannopyranosyl)]-3,4,6-tri-O-benzyl-α-D-mannopyranoside 
• 431981-80-5 3-O-allyl-2,4,6-tri-O-benzoyl-α-D-mannopyranoside trichloroacetimidate 

Downstream Products

• 863914-97-0 benzyl 2-O-[(2,4,6-tri-O-benzoyl-α-D-mannopyranosyl)-(1->3)-(2,4,6-tri-O-benzoyl-α-D-mannopyranosyl)-(1->3)-(2,4,6-tri-O-benzoyl-α-Dmannopyranosyl)]-3,4,6-tri-O-benzyl-α-D-mannopyranoside 
• 863915-16-6 benzyl (3-O-allyl-α-D-mannopyranosyl)-(1->3)-(α-D-mannopyranosyl)-(1->3)-(α-D-mannopyranosyl)-(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranoside) 

Relevant academic research and scientific papers

Synthesis and heparanase inhibitory activity of sulfated mannooligosaccharides related to the antiangiogenic agent PI-88

A stepwise synthetic route to the mannooligosaccharides from the neutral fraction of Pichia holstii phosphomannan hydrolysate, including a tetrasaccharylamine component, was developed using only two or three readily available d-mannose building blocks. Th

SULFATED OLIGOSACCHARIDE DERIVATIVES

The invention relates to compounds which are polysufated oligosaccharide derivatives having activity as inhibitors of heparan sulfate-binding proteins and inhibitors of the enzyme heparanase; methods for the preparation of the compounds; compositions comprising the compounds, and use of the compounds and compositions thereof for the antiangiogenic, antimetastatic, anti-inflammatory, antimicrobial, anticoagulant and/or antithrombotic treatment, lowering of blood triglyceride levels and inhibition of cardiovascular disease of a mammalian subject.