4321-64-6

Basic information

• Product Name: O-methyl O-(3-methyl-4-nitrophenyl) hydrogen phosphorothioate
• CAS NO: 4321-64-6
• Molecular Formula: C₈H₁₀NO₅PS
• Molecular Weight: 263.2075
• Mol File: 4321-64-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 394.1°C at 760 mmHg
• Flash Point: 192.1°C
• Density: 1.483g/cm³
• Vapor Pressure: 6.46E-07mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: O-methyl O-(3-methyl-4-nitrophenyl) hydrogen phosphorothioate(CAS DataBase Reference)
• NIST Chemistry Reference: O-methyl O-(3-methyl-4-nitrophenyl) hydrogen phosphorothioate(4321-64-6)
• EPA Substance Registry System: O-methyl O-(3-methyl-4-nitrophenyl) hydrogen phosphorothioate(4321-64-6)

Safety Data

• Hazardous Substances Data: 4321-64-6(Hazardous Substances Data)

Upstream product

• 122-14-5 MEP 
• 109-73-9 N-butylamine 
• 110-89-4 piperidine 

Relevant articles and documents

Microwave-assisted nucleophilic degradation of organophosphorus pesticides in propylene carbonate

Propylene carbonate is becoming a suitable green alternative to volatile organic solvents in the study of chemical reactions. In this study, an efficient method for nucleophilic degradation of five organophosphorus pesticides, fenitrothion, malathion, diazinon, parathion, and paraoxon, using propylene carbonate as a solvent is proposed. The effect of changing the nature of the nucleophile and the influence of microwave (MW) heating were investigated. A screening of temperatures (50 °C-120 °C) was performed under microwave heating. The pesticide degradation was followed by 31P NMR, and the extent of conversion (%) was calculated by the integration of phosphorus signals. Keeping in mind that recently it has been reported that some ionic liquids play a nucleophilic role, in this work we report for the first time the degradation of organophosphorus pesticides by using an amino acid-based ionic liquid such as Bmim[Ala] as a nucleophile and a bio-based solvent (propylene carbonate) as a reaction medium in combination with microwave heating. This journal is

Stabilization of the pesticide Fenitrothion toward O and N nucleophiles in the presence of cyclodextrins

The reaction of Fenitrothion with O and N nucleophiles (H2O2, NH2OH, n-butylamine and piperidine) was studied at 25°C in water containing 2% 1,4-dioxane in the presence of native cyclodextrins (α-, β-, and γ-CD). For all the nucleophiles, the presence of CD produces reaction inhibition with saturation kinetics. The greatest effect in all cases is observed with β-CD, and the greatest inhibition was observed for the reaction of Fenitrothion with H2O2 (81%), which is the most efficient nucleophile in promoting Fenitrothion degradation in homogeneous media. In the absence of CD, competition between the SN2(P) and the SN2(C) pathways was observed with piperidine as was reported before for the reaction with NH2OH and n-butylamine. The presence of β-CD does not modify product distribution in the case of the reaction with NH2OH and n-butylamine, whereas there is an increase in SN2(C) pathway when the nucleophile is piperidine.

Stereochemistry of Aryl Methyl Phosphorochloridothionates as Chiral Two-step Phosphorylating Reagents

Seven aryl methyl phosphorochloridothionates were prepared and examined for reactivity as two-step phosphorylating reagents to synthesize oxazaphospholidine sulfide.The 2,6-dichloro-4-methylphenyl and p-nitrophenyl derivatives (CMPC and MNPC) were selecte