43219-50-7

Basic information

• Product Name: 1-ISOCYANO-2-METHOXYETHANE
• Synonyms: 2-METHOXYETHYL ISOCYANIDE;1-ISOCYANO-2-METHOXYETHANE;BIO-FARMA BF001978;HANSA ISN-0740
• CAS NO: 43219-50-7
• Molecular Formula: C₄H₇NO
• Molecular Weight: 85.1
• Mol File: 43219-50-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-ISOCYANO-2-METHOXYETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ISOCYANO-2-METHOXYETHANE(43219-50-7)
• EPA Substance Registry System: 1-ISOCYANO-2-METHOXYETHANE(43219-50-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 43219-50-7(Hazardous Substances Data)

Usage

Uses

1-Isocyano-2-methoxyethane is used in preparation of Chitosan-coated liposomes as novel carrier system for mucoadhesive liposomes loaded with antiviral drug triazavirin.

Upstream product

• 43219-53-0 N-formyl-O-methylethanolamine 

Downstream Products

• 1192481-56-3 C₁₇H₁₇ClN₂O₂ 
• 1192481-45-0 C₁₇H₁₈N₂O₂ 
• 1207835-34-4 C₂₀H₂₂N₄OS 
• 1207835-38-8 2-[4-(dimethylamino)phenyl]-N-(2-methoxyethyl)-6-methylimidazo[2,1-b][1,3]benzothiazol-3-amine 
• 1207835-47-9 6-chloro-2-[4-(dimethylamino)phenyl]-N-(2-methoxyethyl)imidazo[2,1-b][1,3]benzothiazol-3-amine 
• 1429014-70-9 C₁₇H₂₀ClN₅O₂ 
• 1429014-71-0 C₂₀H₂₇N₅O₂ 
• 1429014-82-3 C₂₁H₂₉N₅O₂ 
• 570365-12-7 6-methoxy-3-[[1-(2-methoxyethyl)-1H-tetrazol-5-yl][(2-phenylethyl)(phenylmethyl)-amino]methyl]-2(1H)-quinolinone 
• 1373025-44-5 C₂₀H₃₀IN₃O₅ 
• 1346782-72-6 C₁₇H₂₀N₂O₃ 
• 1224564-52-6 C₁₇H₂₃N₅O₂ 
• 1224564-00-4 C₁₃H₁₈ClN₃O 
• 1224563-85-2 C₁₅H₂₃N₃O₃ 

Relevant articles and documents

Simple and efficient: Ethylene glycol isonitrile gold(I) chlorides for the formation and stabilization of gold nanoparticles

Ethylene glycol isonitriles C≡N(CH2CH2O) nCH3 (5a, n = 1; 5b, n = 3; 5c, n = 4) with different chain lengths were prepared by using straightforward synthesis methodologies including the Gabriel synthesis and an Appel-type reaction protocol. Upon treatment with [AuCl(SMe)2], compounds 5a-c gave the corresponding isocyanide gold(I) chlorides [AuCl{C≡N(CH2CH2O) nCH3}] (7a, n = 1; 7b, n = 3; 7c, n = 4). Single-crystal X-ray diffraction studies reveal a polymeric (7a) or dimeric (7c) structure with aurophilic interactions. Gold(I) complexes 7a-c were applied in the formation and stabilization of gold nanoparticles (AuNPs). The isonitriles with their ethylene glycol functionalities, which provide multiple donating capabilities, are able to stabilize the encapsulated gold colloids. The reduction of 7a-c by the addition of Na[BH4] in tetrahydrofuran or methanol produces AuNPs without the further addition of any stabilizer, since metal-organic 7a-c combine the stabilizing component and gold source in one molecule. The dependency of different solvents, concentrations, and varying ethylene glycol chain lengths on the NP size and size distribution is reported. Characterization by TEM, UV/Vis spectroscopy, and XRPD revealed that AuNPs are formed with a size between 6.4(±1.4) to 9.5(±2.3) nm in methanol and 18.2(±2.3) to 27.2(±3.5) nm in tetrahydrofuran. Copyright

Investigations on a carbonyl-olefination with alpha-metallated isocyanides. The synthesis of beta-carotene and other polyenes

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