43228-98-4

Upstream product

• 542-28-9 3,4,5,6-tetrahydro-2H-pyran-2-one 
• 578-57-4 2-bromoanisole 
• 108-55-4 glutaric anhydride, 

Downstream Products

• 1396202-81-5 ethyl 7-(2-methoxyphenyl)-7-oxohept-2-enoate 
• 1396204-24-2 ethyl 2-((2R,6S)-6-(2-methoxyphenyl)tetrahydro-2H-pyran-2-yl)acetate 
• 1396204-36-6 isopropyl 2-((2R,6S)-6-(2-methoxyphenyl)tetrahydro-2H-pyran-2-yl)acetate 
• 389837-61-0 5-(2-methoxyphenyl)-5-oxo-pentanal 
• 124524-69-2 ethyl 5-(2-methoxyphenyl)-5-oxopentanoate 

Relevant academic research and scientific papers

Catalytic asymmetric hydrogenation of δ-ketoesters: Highly efficient approach to chiral 1,5-diols

High turnover: An highly efficient catalytic asymmetric hydrogenation of δ-aryl-δ-ketoesters has been realized by using the chiral spiroiridium catalyst (R)-1. Chiral 1,5-diol products are obtained with excellent enantioselectivity and turnover numbers (TONs) as high as 100 000. TOF=turnover frequency. Copyright

Enantioselective synthesis of 2,6-cis-disubstituted tetrahydropyrans via a tandem catalytic asymmetric hydrogenation/oxa-Michael cyclization: An efficient approach to (-)-centrolobine

A highly efficient one-pot process via a tandem reaction of catalytic asymmetric hydrogenation and oxa-Michael cyclization for the synthesis of 2,6-cis-disubstituted tetrahydropyrans has been developed (ee up to 99.9%, cis/trans-selectivity up to 99:1). T