432522-11-7

Basic information

• Product Name: 1H-Phosphole, 2,3-dihydro-1-(4-methoxyphenyl)-4-methyl-, 1-oxide
• CAS NO: 432522-11-7
• Molecular Formula: C12H15O2P
• Molecular Weight: 222.224
• Mol File: 432522-11-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Phosphole, 2,3-dihydro-1-(4-methoxyphenyl)-4-methyl-, 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Phosphole, 2,3-dihydro-1-(4-methoxyphenyl)-4-methyl-, 1-oxide(432522-11-7)
• EPA Substance Registry System: 1H-Phosphole, 2,3-dihydro-1-(4-methoxyphenyl)-4-methyl-, 1-oxide(432522-11-7)

Safety Data

• Hazardous Substances Data: 432522-11-7(Hazardous Substances Data)

Upstream product

• 18874-22-1 1-chloro-3-methyl-3-phospholene-1-oxide 
• 87243-93-4 1-hydroxy-3-methyl-3-phospholene 1-oxide 
• 695-60-3 1-methoxy-3-methyl-2-phospholene 1-oxide 
• 823-14-3 1-chloro-3-methyl-2-phospholene 1-oxide 
• 13139-86-1 4-methoxyphenyl magnesium bromide 

Downstream Products

• 432522-17-3 1-(4'-methoxy-3,'5'-dinitrophenyl)-3-methyl-2-phospholene 1-oxide 

Relevant articles and documents

Preparation of 2-phospholene oxides by the isomerization of 3-phospholene oxides

A series of 1-substituted-3-methyl-2-phospholene oxides was prepared from the corresponding 3-phospholene oxides by double bond rearrangement. The 2-phospholene oxides could be obtained by heating the 3-phospholene oxides in methanesulfonic acid, or via the formation of cyclic chlorophosphonium salts. Whereas mixtures of the 2- and 3-phospholene oxides formed, when the isomerization of 3-phospholene oxides was attempted under thermal conditions, or in the presence of a base. The mechanisms of the various double bond migration pathways were elucidated by quantum chemical calculations.

Synthesis of novel 1-(substituted phenyl)-2-phospholene 1-oxide derivatives

Several novel 1-(substituted phenyl)-2-phospholene 1-oxide derivatives, which are analogs of sugars having a phosphorus atom in place of the ring oxygen of normal sugars, were synthesized from the corresponding 2-phospholenes as the starting materials. Structures of all the synthesized compounds were unequivocally confirmed by IR, 1H, 13C, and 31P NMR spectral, elemental, and X-ray crystallographic analyses.