433230-57-0

Usage

Physical state

Pale yellow liquid.

Odor

Sweet, floral.

Usage

Commonly used as a fragrance ingredient in perfumes and other personal care products.

Potential applications

Synthesis of pharmaceuticals and other organic compounds.

Manufacturing method

Primarily manufactured through chemical synthesis.

Hazard classification

Moderately hazardous substance.

Handling precautions

Recommendations for proper handling and storage to minimize risks.

Upstream product

• 49769-86-0 methyl 2-(2,5-dimethylphenyl)acetate 
• 13612-34-5 2-(2,5-dimethylphenyl)acetic acid 
• 122-51-0 orthoformic acid triethyl ester 
• 2039-89-6 2,5-dimethylstyrene 

Downstream Products

• 1612882-17-3 C₁₇H₁₆OS₂ 
• 1612882-43-5 C₁₁H₁₅I 
• 1612882-34-4 C₁₁H₁₆O 
• 862205-50-3 {1-[2-(2,5-dimethylphenyl)ethylamino]-4-methyl-2-oxo-1,2-dihydro-pyridin-3-yl}acetic acid methyl ester 

Relevant academic research and scientific papers

Maleimide-assisted anti-Markovnikov Wacker-type oxidation of vinylarenes using molecular oxygen as a terminal oxidant

Arylacetaldehydes were successfully synthesized by the anti-Markovnikov Wacker-type oxidation of vinylarenes using 1 atm O2 as a terminal oxidant under mild conditions. Electron-deficient alkenes, such as maleic anhydride and maleimides, were effective additives and would operate as ligands to stabilize the Pd(0) species during the reaction.

A straightforward organocatalytic alkylation of 2-arylacetaldehydes: An approach towards bisabolanes

A highly stereoselective organocatalytic aalkylation of 2-arylacetaldehydes with a commercially available carbenium tetrafluoroborate is described. The stereoselective alkylation was carried out in acetonitrile/ water, under air in the presence of a commercially available imidazolidinone (MacMillan's catalyst). Key intermediates for the synthesis of bisabolanes were obtained through a simple chemistry. In particular a direct, enantioselective and facile synthesis of (R)-(-)-curcumene is described.

Catalytic oxidation of alkenes with a surface-bound metalloporphyrin- peptide conjugate

A novel surface-bound metalloporphyrin-peptide conjugate was prepared and used to catalytically oxidize alkenes in the presence of iodosylbenzene. The catalyst was found to oxidize a number of alkene substrates in good yield under a variety of reaction conditions. Comparison to control experiments using surface-bound Mn(III)tetraphenylporphyrin showed differences in oxidation yields and ratios of oxidized products. Substrate competition experiments demonstrated the ability of the conjugate catalyst to discriminate between substrates on the basis of size. Both results suggest oxidative catalysis occurred between the porphyrin ring and the peptide chain with the peptide influencing the outcome of the reaction in accord with the catalyst design.