433257-35-3Relevant academic research and scientific papers
A versatile route to (E)- and (Z)-2-hydroxy-3,4-unsaturated disubstituted sulfilimines and their haloamidation reaction
Raghavan, Sadagopan,Mustafa, Shaik,Sridhar
experimental part, p. 4499 - 4507 (2009/09/30)
(Chemical Equation Presented) α-Chloro ynones have been reduced using Noyori's Ru catalyst to furnish R-chloro propargylic alcohols with excellent enantioselectivity. These have been used as a common precursor for the preparation of (E)- and (Z)-2-hydroxy
A practical synthesis of optically active aromatic epoxides via asymmetric transfer hydrogenation of α-chlorinated ketones with chiral rhodium-diamine catalyst
Hamada, Takayuki,Torii, Takayoshi,Izawa, Kunisuke,Ikariya, Takao
, p. 7411 - 7417 (2007/10/03)
A practical method for the synthesis of optically active aromatic epoxides has been developed via the formation of optically active α-chlorinated alcohols and intramolecular etherification. Optically active alcohols with up to 99% ee can be obtained from
Highly enantioselective preparation of multifunctionalized propargylic building blocks
Schubert, Thomas,Hummel, Werner,Mueller, Michael
, p. 634 - 637 (2007/10/03)
Halogenated propargylic alcohol 2a (X = Cl, R = Ph) was prepared by the enzymatic reduction of the corresponding ketone 1a with excellent enantioselectivity and chemical yield. Both enantiomers were synthesized with high total turnover numbers of the cata
