4333-50-0

Basic information

• Product Name: (E)-1-Methyl-4-(1-phenylprop-1-en-1-yl)benzene
• Synonyms: (E)-1-Methyl-4-(1-phenylprop-1-en-1-yl)benzene
• CAS NO: 4333-50-0
• Molecular Weight: 208.303
• Mol File: 4333-50-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-1-Methyl-4-(1-phenylprop-1-en-1-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-Methyl-4-(1-phenylprop-1-en-1-yl)benzene(4333-50-0)
• EPA Substance Registry System: (E)-1-Methyl-4-(1-phenylprop-1-en-1-yl)benzene(4333-50-0)

Safety Data

• Hazardous Substances Data: 4333-50-0(Hazardous Substances Data)

Usage

Description

(E)-1-Methyl-4-(1-phenylprop-1-en-1-yl)benzene, also known as pseudosyndone, is an aromatic hydrocarbon with the molecular formula C18H18. It is a chemical compound that has garnered interest due to its potential applications in various fields.

Uses

Used in Organic Synthesis:
(E)-1-Methyl-4-(1-phenylprop-1-en-1-yl)benzene is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for further chemical reactions to create a wide range of products.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (E)-1-Methyl-4-(1-phenylprop-1-en-1-yl)benzene is utilized as a precursor for the production of different drugs and pharmaceuticals. Its potential applications in drug development make it a valuable compound for research and development efforts.
Used in Medicinal Chemistry:
(E)-1-Methyl-4-(1-phenylprop-1-en-1-yl)benzene has been studied for its potential biological activities and pharmacological properties. Its role in medicinal chemistry is significant, as it may contribute to the discovery of new therapeutic agents and treatments for various diseases and conditions.

Upstream product

• 591-51-5 phenyllithium 
• 5337-93-9 4'-methylpropiophenone 
• 1235751-66-2 3-ethyl-3-phenyl-3H-diazirine 
• 5720-05-8 4-methylphenylboronic acid 
• 74-96-4 ethyl bromide 
• 134-84-9 4-Methylbenzophenone 

Downstream Products

• 34835-98-8 1-phenyl-1-p-tolyl-propane 

Relevant articles and documents

Stereoselective Synthesis of Trisubstituted Vinylboronates from Ketone Enolates Triggered by 1,3-Metalate Rearrangement of Lithium Enolates

An unprecedented stereoselective synthesis of trisubstituted vinylboronates is reported to proceed by direct borylation of lithium ketone enolates under transition-metal-free conditions. The stereospecific C?O borylation of lithium enolates was triggered by a carbonyl-induced 1,3-metalate rearrangement via a C-bound boron enolate. DFT calculations and control experiments revealed that the stereoselectivity is controlled by sterics. A variety of stereospecific trisubstituted vinylboronates, together with several tetrasubstituted vinylboronates, were conveniently synthesized with the newly developed methodology. Based on the transformation of stereospecific vinylboronate, a single isomer of Dienestrol was efficiently obtained.

Synthesis and Reactions of Sulfenic Trifluoromethanesulfonic Anhydrides

Sulfenyl halogenides 1 and 4 react with silver trifluoromethanesulfonate (2) to give aryl 3 and alkylsulfenic trifluoromethanesulfonic anhydrides 5, resp., in good yields; 3 and 5 could not be isolated because of their instability. 1H NMR spectroscopic data of 5a, b, each in dichloromethane and nitromethane, resp., are indicative of a dissoziation to adducts of alkylsulfenylium ions and the solvent.Whereas 3 do not react with aromatic compounds, addition products with diphenylacetylene, arylsulfenylvinyl trifluoromethanesulfonates 11, are formed smoothly, which under the reaction conditions immediately cyclize to give benzothiophenes 10 in excellent yields.