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Upstream product

• 38512-04-8 N-benzyl(1-phenylpropylidene)amine 
• 93-55-0 1-phenyl-propan-1-one 

Downstream Products

• 637-50-3 1-phenylpropene 
• 61574-05-8 C₉H₁₀ 
• 778-66-5 1,1-diphenyl-1-propene 
• 19810-20-9 4-methoxy-α-phenyl-β-methylstyrene 
• 4333-82-8 (Z)-1-methyl-2-(1-phenylprop-1-en-1-yl)benzene 
• 4333-81-7 (E)-1-methyl-2-(1-phenylprop-1-enyl)benzene 
• 4332-16-5 (Z)-1,3,5-trimethyl-2-(1-phenylprop-1-enyl)benzene 
• 4332-15-4 (E)-1,3,5-trimethyl-2-(1-phenylprop-1-enyl)benzene 
• 938-78-3 (1,1-difluorobut-1-en-2-yl)benzene 
• 4333-51-1 1-methyl-4-(1-phenylprop-1-en-1-yl)benzene 
• 4333-50-0 (E)-1-methyl-4-(1-phenylprop-1-en-1-yl)benzene 
• 304477-62-1 1-chloro-4-(1-phenylprop-1-enyl)benzene 
• 304477-64-3 1-chloro-4-(1-phenylprop-1-enyl)benzene 

Relevant academic research and scientific papers

Metal-free oxidative cross-coupling of diazirines with arylboronic acids

We report herein a metal-free cross-coupling of diazirines with arylboronic acids under oxidative conditions. The reaction affords a series of substituted olefins. It is proposed that the interaction between the nitrogen on diazirine with arylboronic acid plays a key role in this transformation.

gem-Difluoroolefination of Diazo Compounds with TMSCF3 or TMSCF2Br: Transition-Metal-Free Cross-Coupling of Two Carbene Precursors

A new olefination protocol for transition-metal-free cross-coupling of two carbene fragments arising from two different sources, namely, a nonfluorinated carbene fragment resulting from a diazo compound and a difluorocarbene fragment derived from Ruppert-Prakash reagent (TMSCF3) or TMSCF2Br, has been developed. This gem-difluoroolefination proceeds through the direct nucleophilic addition of diazo compounds to difluorocarbene followed by elimination of N2. Compared to previously reported Cu-catalyzed gem-difluoroolefination of diazo compounds with TMSCF3, which possesses a narrow substrate scope due to a demanding requirement on the reactivity of diazo compounds and in-situ-generated CuCF3, this transition-metal-free protocol affords a general and efficient approach to various disubstituted 1,1-difluoroalkenes, including difluoroacrylates, diaryldifluoroolefins, as well as arylalkyldifluoroolefins. In view of the ready availability of diazo compounds and difluorocarbene reagents and versatile transformations of 1,1-difluoroalkenes, this new gem-difluoroolefination method is expected to find wide applications in organic synthesis.

Microwave-assisted, Pd(0)-catalyzed cross-coupling of diazirines with aryl halides

Pd(0)-catalyzed cross-coupling reactions of diazirines with aryl halides under microwave heating conditions afford a series of substituted olefins. A reaction mechanism involving the migratory insertion of the Pd carbene intermediate is proposed.