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2',3'-Dehydroadenosine is a modified nucleoside that is structurally similar to adenosine, a naturally occurring nucleoside found in DNA and RNA. It is characterized by the absence of two hydrogen atoms at the 2' and 3' positions of the ribose sugar moiety, which results in the formation of a double bond between these positions. This modification can significantly alter the chemical properties and biological activities of the nucleoside. In the context of medicinal chemistry, 2',3'-dehydroadenosine and its derivatives have been studied for their potential antiviral and anticancer properties, as well as their ability to modulate immune responses. The unique structure of 2',3'-dehydroadenosine can lead to different interactions with enzymes and receptors compared to the parent compound adenosine, making it a subject of interest in drug development.

4336-89-4

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4336-89-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4336-89-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,3 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4336-89:
(6*4)+(5*3)+(4*3)+(3*6)+(2*8)+(1*9)=94
94 % 10 = 4
So 4336-89-4 is a valid CAS Registry Number.

4336-89-4Upstream product

4336-89-4Downstream Products

4336-89-4Relevant academic research and scientific papers

NEW 2' AND/OR 5' AMINO-ACID ESTER PHOSPHORAMIDATE 3'-DEOXY ADENOSINE DERIVATIVES AS ANTI-CANCER COMPOUNDS

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Page/Page column 57, (2016/06/14)

The present invention relates to chemical compounds, the compounds for use in a method of treatment, particularly in a method of prophylaxis or treatment for cancer, a process for preparation of the compounds and pharmaceutical compositions comprising the compounds. The compounds may, in particular, be useful in the treatment of leukaemia, lymphoma and/or solid tumours inhomo sapiens. The compounds are derivatives of cordycepin (3'-deoxyadenosine) having a 2' and/or 5'- amino-acid ester phosphoramidate moeity.

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