433711-90-1

Upstream product

• 433711-83-2 {(2S)-methoxy-(1R)-[1-(4-methoxybenzyl)-5-oxo-(3S)-Z-propenylpyrrolidin-(2R)-yl]-(2S)-methylpentyl}-carbamic acid tert-butyl ester 
• 176108-62-6 (R)-4-but-3-enoyl-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 
• 433711-84-3 N-{(2S)-methoxy-(1R)-[1-(4-methoxybenzyl)-5-oxo-(3S)-Z-propenylpyrrolidin-(2R)-yl]-(2S)-methylpentyl}-acetamide 
• 433711-82-1 (5R)-tert-butoxycarbonylamino-(4R)-[hydroxy-(4-methoxybenzyl)-amino]-(6S)-methoxy-(6S)-methylnon-2-ynoic acid tert-butyl ester 
• 433711-81-0 (5R)-tert-butoxycarbonylamino-(4R)-[hydroxy-(4-methoxybenzyl)-amino]-(6S)-methoxy-(6S)-methylnon-2-ynoic acid ethyl ester 
• 335693-89-5 {(2S)-methoxy-(1R)-[1'-(4-methoxybenzyl)-5'-oxo-2',5'-dihydro-1H-pyrrol-(2'R)-yl]-(2S)-methylpentyl}-carbamic acid tert-butyl ester 
• 335693-80-6 C₂₁H₃₄N₂O₅ 
• 433711-93-4 (R)-4-((S)-1-Methoxy-1-methyl-butyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 433711-79-6 (4R,1'S)-4-(1-hydroxy-1-methyl-butyl)-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 
• 335693-71-5 ((1R,2S)-1-Hydroxymethyl-2-methoxy-2-methyl-pentyl)-carbamic acid tert-butyl ester 
• 335693-75-9 (1S,2S)-(1-formyl-2-methoxy-2-methylpentyl)-carbamic acid tert-butyl ester 
• 51307-59-6 N-(4-methoxybenzyl)hydroxylamine 

Downstream Products

• 433711-84-3 N-{(2S)-methoxy-(1R)-[1-(4-methoxybenzyl)-5-oxo-(3S)-Z-propenylpyrrolidin-(2R)-yl]-(2S)-methylpentyl}-acetamide 
• 335679-69-1 A-315675 

Relevant academic research and scientific papers

COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS

Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).

Total synthesis of A-315675: A potent inhibitor of influenza neuraminidase

A concise, stereocontrolled, and practical synthesis of a neuraminidase inhibitor consisting of a highly functionalized D-proline scaffold is described. Key features involve a stereocontrolled addition of a propiolate ester to a chiral nonracemic nitrone