433711-83-2

Upstream product

• 433711-82-1 (5R)-tert-butoxycarbonylamino-(4R)-[hydroxy-(4-methoxybenzyl)-amino]-(6S)-methoxy-(6S)-methylnon-2-ynoic acid tert-butyl ester 
• 433711-81-0 (5R)-tert-butoxycarbonylamino-(4R)-[hydroxy-(4-methoxybenzyl)-amino]-(6S)-methoxy-(6S)-methylnon-2-ynoic acid ethyl ester 
• 335693-80-6 C₂₁H₃₄N₂O₅ 
• 335693-71-5 ((1R,2S)-1-Hydroxymethyl-2-methoxy-2-methyl-pentyl)-carbamic acid tert-butyl ester 
• 167102-62-7 (R)-N,O-isopropylidenyl-2-(N-tert-butyloxycarbonylamino)-3-oxo-propanamide-N,O-dimethyl-hydroxyamine 
• 51307-59-6 N-(4-methoxybenzyl)hydroxylamine 
• 6524-17-0 (Z)-1-propenyllithium 
• 335693-89-5 {(2S)-methoxy-(1R)-[1'-(4-methoxybenzyl)-5'-oxo-2',5'-dihydro-1H-pyrrol-(2'R)-yl]-(2S)-methylpentyl}-carbamic acid tert-butyl ester 
• 433711-93-4 (R)-4-((S)-1-Methoxy-1-methyl-butyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 433711-79-6 (4R,1'S)-4-(1-hydroxy-1-methyl-butyl)-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 
• 335693-75-9 (1S,2S)-(1-formyl-2-methoxy-2-methylpentyl)-carbamic acid tert-butyl ester 
• 176108-62-6 (R)-4-but-3-enoyl-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 

Downstream Products

• 433711-84-3 N-{(2S)-methoxy-(1R)-[1-(4-methoxybenzyl)-5-oxo-(3S)-Z-propenylpyrrolidin-(2R)-yl]-(2S)-methylpentyl}-acetamide 
• 335679-69-1 A-315675 
• 433711-90-1 (4S,5R)-5-((1R,2S)-1-Amino-2-methoxy-2-methyl-pentyl)-1-(4-methoxy-benzyl)-4-((Z)-propenyl)-pyrrolidin-2-one 

Relevant academic research and scientific papers

Total synthesis of A-315675: A potent inhibitor of influenza neuraminidase

A concise, stereocontrolled, and practical synthesis of a neuraminidase inhibitor consisting of a highly functionalized D-proline scaffold is described. Key features involve a stereocontrolled addition of a propiolate ester to a chiral nonracemic nitrone