433726-44-4

Basic information

• Product Name: 4-[2-(6-oxo-6,7,8,9-tetrahydro-2,7,9a-triaza-benzo[cd]azulen-1-yl)-ethyl]-benzoic acid ethyl ester
• Synonyms: 4-[2-(6-oxo-6,7,8,9-tetrahydro-2,7,9a-triaza-benzo[cd]azulen-1-yl)-ethyl]-benzoic acid ethyl ester
• CAS NO: 433726-44-4
• Molecular Weight: 363.416
• Mol File: 433726-44-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[2-(6-oxo-6,7,8,9-tetrahydro-2,7,9a-triaza-benzo[cd]azulen-1-yl)-ethyl]-benzoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-(6-oxo-6,7,8,9-tetrahydro-2,7,9a-triaza-benzo[cd]azulen-1-yl)-ethyl]-benzoic acid ethyl ester(433726-44-4)
• EPA Substance Registry System: 4-[2-(6-oxo-6,7,8,9-tetrahydro-2,7,9a-triaza-benzo[cd]azulen-1-yl)-ethyl]-benzoic acid ethyl ester(433726-44-4)

Safety Data

• Hazardous Substances Data: 433726-44-4(Hazardous Substances Data)

Upstream product

• 328546-65-2 9-nitro-1,2,3,4-tetrahydro-5H-1,4-benzodiazepin-5-one 
• 53553-14-3 2-chloro-3-nitrobenzoic acid methyl ester 
• 151864-81-2 ethyl 4-(3-oxopropyl)benzoate 
• 328546-66-3 9-amino-1,2,3,4-tetrahydro-5H-benzo[e][1,4]diazepin-5-one 

Downstream Products

• 433728-62-2 1-[2-(4-chloromethyl-phenyl)-ethyl]-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one 
• 433726-45-5 1-[2-(4-hydroxymethyl-phenyl)-ethyl]-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one 

Relevant articles and documents

Design and synthesis of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. Part 4: Biological evaluation of imidazobenzodiazepines as potent PARP-1 inhibitors for treatment of ischemic injuries

A class of poly(ADP-ribose) polymerase (PARP-1) inhibitors, the imidazobenzodiazepines, are presented in this text. Several derivatives were designed and synthesized with ionizable groups (i.e., tertiary amines) in order to promote the desired pharmaceuti