328546-65-2

Usage

Chemical Properties

Orange crystalline

InChI:InChI=1/C9H9N3O3/c13-9-6-2-1-3-7(12(14)15)8(6)10-4-5-11-9/h1-3,10H,4-5H2,(H,11,13)

Upstream product

• 50349-89-8 8-nitro-2,3-dihydroquinoline-4(1H)-one 
• 5337-09-7 2-bromo-3-nitro-benzoic acid methyl ester 
• 107-15-3 ethylenediamine 
• 53553-14-3 2-chloro-3-nitrobenzoic acid methyl ester 
• 4013-43-8 ethylene-1,2-diamine 
• 6780-13-8 1,2-ethanediamine monohydrate 
• 71-36-3 butan-1-ol 
• 79-37-8 oxalyl dichloride 
• 573-54-6 2-bromo-3-nitro-benzoic acid 

Downstream Products

• 433728-54-2 1-benzoyl-9-nitro-1,2,3,4-tetrahydro-benzo[e][1,4]diazepin-5-one 
• 328542-04-7 1-Phenyl-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one 
• 433726-95-5 8,9-dihydro-2,7,9a-triazabenzo[cd]azulen-6(7H)-one 
• 433726-34-2 3-(6-oxo-6,7,8,9-tetrahydro-2,7,9a-triaza-benzo[cd]azulen-1-yl)-benzoic acid 
• 433726-45-5 1-[2-(4-hydroxymethyl-phenyl)-ethyl]-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one 
• 433728-62-2 1-[2-(4-chloromethyl-phenyl)-ethyl]-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one 
• 433726-44-4 4-[2-(6-oxo-6,7,8,9-tetrahydro-2,7,9a-triaza-benzo[cd]azulen-1-yl)-ethyl]-benzoic acid ethyl ester 
• 641637-70-9 [1-(6-oxo-6,7,8,9-tetrahydro-2,7,9a-triaza-benzo[cd]azulen-1-yl)-2-phenyl-ethyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

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The present invention provides a compound of formula I or II or a pharmaceutically acceptable salt form thereof, wherein R1, R2, R3, R4, R5, A1, A2, A3, A4, and A5, are as defined herein. The compounds of formula I or II have ALK and/or c-Met inhibitory activity, and may be used to treat proliferative disorders.

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Design and synthesis of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. Part 4: Biological evaluation of imidazobenzodiazepines as potent PARP-1 inhibitors for treatment of ischemic injuries

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