433981-16-9

Upstream product

• 272104-64-0 methyl 3-bromomethyl-2-phenylquinoline-4-carboxylate 
• 74960-43-3 3-methyl-2-phenyl-quinoline-4-carboxylic acid methyl ester 
• 174636-71-6 3-methyl-2-phenylquinoline-4-carbonyl chloride 
• 43071-45-0 3-methyl-2-phenylquinoline-4-carboxylic acid 
• 345235-09-8 3-[4-(9H-fluoren-9-ylmethoxycarbonylamino)-piperidin-1-ylmethyl]-2-phenyl-quinoline-4-carboxylic acid methyl ester 

Downstream Products

• 345235-03-2 {1-[4-((S)-1-Cyclohexyl-ethylcarbamoyl)-2-phenyl-quinolin-3-ylmethyl]-piperidin-4-yl}-carbamic Acid 9H-fluoren-9-ylmethyl Ester 

Relevant academic research and scientific papers

Stepwise modulation of neurokinin-3 and neurokinin-2 receptor affinity and selectivity in quinoline tachykinin receptor antagonists

A stepwise chemical modification from human neurokinin-3 receptor (hNK-3R)-selective antagonists to potent and combined hNK-3R and hNK-2R antagonists using the same 2-phenylquinoline template is described. Docking studies with 3-D models of the hNK-3 and