434-02-6

Basic information

• Product Name: (11beta)-21-fluoro-11,17-dihydroxypregn-4-ene-3,20-dione
• Synonyms: 21-FLUORO-11B,17-DIHYDROXYPREGN-4-ENE-3,20-DIONE; Progesterone, 21-fluoro-11.beta.,17-dihydroxy-
• CAS NO: 434-02-6
• Molecular Formula: C₂₁H₂₉FO₄
• Molecular Weight: 364.451
• Mol File: 434-02-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 538°C at 760 mmHg
• Flash Point: 279.2°C
• Density: 1.26g/cm³
• Vapor Pressure: 8.1E-14mmHg at 25°C
• Refractive Index: 1.565
• CAS DataBase Reference: (11beta)-21-fluoro-11,17-dihydroxypregn-4-ene-3,20-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (11beta)-21-fluoro-11,17-dihydroxypregn-4-ene-3,20-dione(434-02-6)
• EPA Substance Registry System: (11beta)-21-fluoro-11,17-dihydroxypregn-4-ene-3,20-dione(434-02-6)

Safety Data

• Hazardous Substances Data: 434-02-6(Hazardous Substances Data)

Usage

General Description

"(11beta)-21-fluoro-11,17-dihydroxypregn-4-ene-3,20-dione" is a synthetic corticosteroid that belongs to the class of glucocorticoids. It is a derivative of the natural hormone cortisol, with an added fluorine atom at the 21st position. This chemical has anti-inflammatory and immunosuppressant properties, and it is commonly used in the treatment of various inflammatory and autoimmune conditions such as rheumatoid arthritis, asthma, and dermatitis. Its mechanism of action involves binding to glucocorticoid receptors and modulating gene expression, leading to a reduction in inflammation and immune response. Additionally, it has mineralocorticoid activity, meaning it can affect electrolyte balance and fluid regulation in the body.

Upstream product

• 6677-96-9 11β,7α-dihydroxy-21-<(methylsulfonyl)oxy>pregn-4-ene-3,20-dione 
• 33767-06-5 11β,17α-dihydroxy-21-iodopregn-4-ene-3,20-dione