4341-11-1

Upstream product

• 148-24-3 8-quinolinol 
• 100-01-6 4-nitro-aniline 
• 100-05-0 4-nitrobenzenediazonium chloride 

Downstream Products

• 129890-95-5 (dicyclohexyldithiophosphato)(5-(p-nitrophenylazo)-8-hydroxyquinolinato)nickel(II) 

Relevant academic research and scientific papers

A comprehensive spectroscopic, solvatochromic and photochemical analysis of 5-hydroxyquinoline and 8-hydroxyquinoline mono-azo dyes

A series of novel substituted-azo dyes 8-(aryldiazenyl)quinolin-5-ol (5a-i) were synthesized by the coupling reaction of 5-hydroxyquinoline with diazotized aniline derivatives in the presence of NaNO2 in HCl/H2O mixture. The study of

Quinoline azo derivative sensor based on hydroxyl deprotection reaction and preparation and application of quinoline azo derivative sensor

The invention discloses a quinoline azo derivative sensor based on hydroxyl deprotection reaction and preparation and application of the quinoline azo derivative sensor. P-nitroaniline, tert-butyl dimethyl chlorosilane, 8-hydroxyquinoline and the like are used as raw materials to prepare tert-butyl dimethyl-p-nitroaniline azo 8-hydroxyquinoline, and the tert-butyl dimethyl-p-nitroaniline azo 8-hydroxyquinoline is marked as P-TB. An infrared spectrometer, an ultraviolet-visible spectrophotometer and a fluorescence spectrometer are used for carrying out structure and performance characterizationon a product, and the spectral change rule and the anion recognition behavior of the product are explored. Results show that the P-TB acetonitrile solution can identify F in methanol and an aqueous solution. According to the invention, a fluorine ion photochemical identification method is expanded; the preparation method of the sensor is novel and simple, ion recognition equipment is simple,operation is convenient, the operation steps of photochemical ion recognition are greatly reduced, the sensor can be applied to fluorine ion detection in the fields of medicine, environment, water andthe like, the detection cost is greatly saved, the environment is protected, and good economic and social benefits are achieved.

Synthesis of mordant azo dyes using supported Diazonium ions and br?nsted acidic ionic liquids

Diazonium ions supported on Amberlite IR120 (Na+) have been prepared and used for the synthesis of a variety of 5-arylazo-8-hydroxyquinoline in solid state as well as in pyridinium based ionic liquids under microwave heating. The two methods have been compared with respect to ease of recovery, yield, reaction time and environmental impact.

Thermal properties, geometrical structures, antimicrobial activity and DNA binding of supramolecular azo dye complexes

Ru(III) complexes of 5-(4-derivative phenyl azo)-8-hydroxyquinoline (HLn) are prepared and characterized by elemental analyses, IR, UV-Visible spectra, 1H and 13C NMR spectra, mass spectra, X-ray diffraction analysis, conductivity measurements and magnetic susceptibility measurements as well as thermal analysis. The XRD patterns show that the ligand (HL3) has a polycrystalline nature and complex (2) is completely amorphous. The ligands act as a monobasic bidentate coordinating through CN and OH groups by replacement of a proton from the latter group. The molar conductivities show that the Ru(III) complexes are non-electrolyte in nature. The spectra show that all complexes are octahedral in which two chlorides are attached to the metal ion. The optimized bond lengths, bond angles and the calculated quantum chemical parameters for the ligands (HLn) and Ru(III) complexes are investigated. Molecular docking was used to predict the binding between azo dye ligands and the receptor of prostate cancer mutant 2q7k-hormone. The activation thermodynamic parameters, such as activation energy (Ea), enthalpy (ΔH?), entropy (Δ?) and Gibbs free energy change of the decomposition (ΔG?) are calculated using Coats-Redfern and Horowitz-Metzger methods. The ligands (HLn) and Ru(III) complexes are screened for their antimicrobial activity against bacterial and fungal species. The tested complexes (1) and (2) have good antibacterial activity against Bacillus cereus and the tested ligands (HL2, HL3 and HL5) have good antifungal activity against Aspergillus Niger and also HL5 showed against Alternaria alternata. The catalytic oxidation of cyclohexanol by [Ru(Ln)(AsPh3)2Cl2]·xH2O with periodic acid as co-oxidant is described. The Ru(III) complexes exhibited a catalytic activity for the oxidation of cyclohexanol to cyclohexanon.

Geometrical structures, thermal, optical and electrical properties of azo quinoline derivatives

Azo quinoline derivatives (AQx) were synthesized by coupling of 8-hydroxyquinoline with aniline derivatives. The optimized bond lengths, bond angles and the quantum chemical parameters for the ligands (AQx) were calculated. The dielectric constants (εr and εi) and ac conductivity (σac) were studied as a function of both temperature and frequency in the temperature range 293-509 K and frequency range 102-105 Hz. The thermal activation energies ΔE1 and ΔE2 were calculated and found to be in the range of 0.03-0.26 and 0.2-1.31 eV, respectively, depending on the substituent and frequency. The conduction mechanism was investigated for all the derivatives under investigation. The ligands (AQ1, AQ2 and AQ4) were found to be controlled by correlated barrier hopping model and the ligands (AQ3 and AQ5) were controlled by small polaron tunneling mechanism. The optical absorption properties of the ligands thin films were investigated. The absorption coefficient (α) spectra reveals two absorption peaks which are assigned as π-π? and n-π? transitions. The optical energy gap (Eg) was investigated near the absorption edge and found to be in the range of 1.34-2.26 and 1.47-1.69 eV for direct and indirect optical transitions, respectively.

Azo-8-hydroxyquinoline dyes: The synthesis, characterizations and determination of tautomeric properties of some new phenyl- and heteroarylazo-8-hydroxyquinolines

Two series of new heterocyclic and carbocyclic disperse azo dyes based on 8-hydroxyquinoline were prepared and characterized by FT-IR, 1H NMR, mass spectroscopic techniques and elemental analysis. Their solvatochromic properties in different solvents were investigated and their absorption spectra were strongly solvent dependent. The acid and base effects on this equilibrium were also examined. In addition, the colors of dyes were discussed with respect to the nature of the carbocyclic and heterocyclic rings and substituent therein. To determine the tautomeric forms of the prepared dyes in solid state, X-ray data for 5-(5-methylthiazol-2-yldiazenyl)-8-hydroxyquinoline were recorded. The X-ray results showed that the dye exists as an azo tautomer in the solid state.

One-pot diazo coupling reaction under microwave irradiation in the absence of solvent

Diazotization and coupling reactions were carried out in one pot by inducing with microwave irradiation in the absence of solvent.