434331-68-7

Upstream product

• 81477-94-3 N-(diphenylmethylene)glycine tert-butyl ester 
• 922-67-8 propynoic acid methyl ester 

Downstream Products

• 342376-59-4 (Z)-2-(Benzhydrylidene-amino)-pent-2-enedioic acid 1-tert-butyl ester 5-[(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl] ester 
• 434331-73-4 (Z)-2-(benzhydrylideneamino)-4-methylpent-2-enedioic acid 1-tert-butyl 5-methyl ester 
• 434331-74-5 (Z)-2-(benzhydrylideneamino)-4-benzylpent-2-enedioic acid 1-tert-butyl 5-methyl ester 
• 342376-63-0 (Z)-(R)-2-(Benzhydrylidene-amino)-5-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-4-(4-nitro-benzyl)-5-oxo-pent-2-enoic acid tert-butyl ester 
• 342376-62-9 (Z)-(R)-2-(Benzhydrylidene-amino)-4-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-hex-2-enedioic acid 1-tert-butyl ester 6-ethyl ester 
• 342376-61-8 (Z)-(R)-2-(Benzhydrylidene-amino)-4-benzyl-5-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-5-oxo-pent-2-enoic acid tert-butyl ester 
• 342376-60-7 (Z)-(R)-2-(Benzhydrylidene-amino)-5-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-4-methyl-5-oxo-pent-2-enoic acid tert-butyl ester 
• 434331-90-5 5-benzyl-1-tert-butoxycarbonylmethyl-6-oxo-1,4,5,6-tetrahydropyridazine-3-carboxylic acid tert-butyl ester 
• 434332-11-3 1-benzyl-6-oxoperhydropyridazine-3-carboxylic acid tert-butyl ester 
• 434331-98-3 1-benzyl-6-oxo-1,4,5,6-tetrahydropyridazine-3-carboxylic acid tert-butyl ester 
• 434331-82-5 5-benzyl-6-oxo-1,4,5,6-tetrahydropyridazine-3-carboxylic acid tert-butyl ester 
• 342376-58-3 (Z)-2-(Benzhydrylidene-amino)-5-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-5-oxo-pent-2-enoic acid tert-butyl ester 

Relevant academic research and scientific papers

Conformationally restricted glutamic acid derivatives: Asymmetric synthesis of 4-substituted 4,5-dihydro-3(2H)-pyridazinones

The synthesis of optically pure 4,5-dihydro-3(2H)-pyridazinones substituted at C-4, which can be considered conformationally restricted cyclic Glu derivatives, has been accomplished by the asymmetric γ-alkylation of α,β-unsaturated glutamyl sultams under PTC conditions followed by reaction with hydrazines.