434957-82-1

Basic information

• Product Name: Methyl (S)-3-acetamido-3-(4-methoxyphenyl)propanoate
• Synonyms: (S)-METHYL 3-ACETAMIDO-3-(4-METHOXYPHENYL) PROPANOATE;METHYL (S)-3-ACETAMIDO-3-(4-METHOXYPHENYL)PROPANOATE
• CAS NO: 434957-82-1
• Molecular Formula: C13H17NO4
• Molecular Weight: 251.28
• Product Categories: API intermediates
• Mol File: 434957-82-1.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 440.3 °C at 760 mmHg
• Flash Point: 220.1 °C
• Appearance: /
• Density: 1.129 g/cm³
• Refractive Index: 1.508
• CAS DataBase Reference: Methyl (S)-3-acetamido-3-(4-methoxyphenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl (S)-3-acetamido-3-(4-methoxyphenyl)propanoate(434957-82-1)
• EPA Substance Registry System: Methyl (S)-3-acetamido-3-(4-methoxyphenyl)propanoate(434957-82-1)

Safety Data

• Hazardous Substances Data: 434957-82-1(Hazardous Substances Data)

Usage

General Description

Methyl (S)-3-acetamido-3-(4-methoxyphenyl)propanoate is a chemical compound with the molecular formula C13H17NO4. It is a chiral compound, meaning it has a non-superimposable mirror image, and the (S)- designation indicates that it has a specific spatial arrangement of atoms. Methyl (S)-3-acetamido-3-(4-methoxyphenyl)propanoate is commonly used as an intermediate in the synthesis of pharmaceuticals, particularly in the production of drugs with analgesic and anti-inflammatory properties. Methyl (S)-3-acetamido-3-(4-methoxyphenyl)propanoate may also have potential applications in other industries, including the development of new materials and in research and development activities.

InChI:InChI=1/C13H17NO4/c1-9(15)14-12(8-13(16)18-3)10-4-6-11(17-2)7-5-10/h4-7,12H,8H2,1-3H3,(H,14,15)/t12-/m0/s1

Upstream product

• 108-24-7 acetic anhydride 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 22027-50-5 methyl 3-(4-methoxybenzoyl)acetate 
• 654061-84-4 methyl 3-amino-3-(4-methoxyphenyl)acrylate 
• 434957-24-1 (Z)-methyl 3-acetamido-3-(4-methoxyphenyl)-2-propenoate 
• 552838-52-5 methyl 3-acetamido-3-(4-methoxyphenyl)-2-propenoate 
• 1333-74-0 hydrogen 

Relevant articles and documents

Nickel-catalyzed enantioselective umpolung hydrogenation for stereoselective synthesis of β-amido esters

Nickel complexes ligated by strongly donating diphosphines catalyze enantioselective hydrogenation for the preparation of acyclic and cyclic β-amido esters. A combination of acetic acid and indium powder provides protons and electrons to form nickel hydrido complexes under umpolung hydrogenation conditions.

Nickel-catalyzed asymmetric transfer hydrogenation of olefins for the synthesis of α- And β-amino acids

The field of asymmetric (transfer) hydrogenation of prochiral olefins has been dominated by noble metal catalysts based on rhodium, ruthenium, and iridium. Herein we report that a simple nickel catalyst is highly active in the transfer hydrogenation using

Readily available chiral phosphine-aminophosphine ligands derived from 1-phenylethylamine for Rh-catalyzed enantioselective hydrogenations

A series of new chiral phosphine-aminophosphine ligands have been prepared via a two- or three-step transformation from commercially available and inexpensive (S)-1-phenylethylamine, and successfully used in the rhodium-catalyzed asymmetric hydrogenation