4350-74-7Relevant articles and documents
COMPOUNDS AND METHODS OF TREATING OCULAR DISORDERS
-
Paragraph 00193, (2016/06/14)
A method of treating an ocular disorder in a subject associated with increased all-trans-retinal in an ocular tissue includes administering to the subject a therapeutically effective amount of a primary amine compound of formula (I); and pharmaceutically acceptable salts thereof.
Fast preparation of dihydrocyclocitral from citronellal under solventless microwave irradiation
Nhuan, Ngoc Doan,Thach, Ngoc Le,Poul, Erik Hansen,Duus, Fritz
, p. 6749 - 6751 (2007/10/03)
Dihydrocyclocitral, a useful reagent in organic synthesis, has been synthesized in high yield and with high stereoselectivity from citronellal under microwave irradiation in two steps, involving acetic anhydride under base catalysis, then p-toluenesulfonic acid adsorbed on silica gel under solventless conditions (80% yield, reaction time 22 min).
Aldehyde Enol Esters as Novel Chain Terminators in Cationic Olefin Cyclizations
Simmons, Dana P.,Reichlin, Daniel,Skuy, David
, p. 1000 - 1004 (2007/10/02)
Citronellal (1) has been transformed into enol acetates 2 which have been cyclized with various Lewis and Broensted acids to dihydrocyclocitral (4).Application of this methodology to the synthesis of mono- and bicyclic ring systems has been examined.