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Cyclohexane monocarboxylic acid β-lactone, also known as 6-oxabicyclo[3.1.0]hexane-2-carboxylic acid, is a cyclic organic compound with the molecular formula C7H10O3. It features a six-membered cyclohexane ring with a β-lactone group (a four-membered lactone ring) attached to one of the carbon atoms. cyclohexane monocarboxylic acid β-lactone is an important intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals due to its unique structure and reactivity. It can be synthesized through various methods, including the reaction of cyclohexanone with chloroacetic acid or the intramolecular cyclization of 6-hydroxyhexanoic acid. Cyclohexane monocarboxylic acid β-lactone is known for its stability and can undergo various chemical transformations, making it a valuable building block in organic synthesis.

4350-82-7

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4350-82-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4350-82-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,5 and 0 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4350-82:
(6*4)+(5*3)+(4*5)+(3*0)+(2*8)+(1*2)=77
77 % 10 = 7
So 4350-82-7 is a valid CAS Registry Number.

4350-82-7Upstream product

4350-82-7Downstream Products

4350-82-7Relevant academic research and scientific papers

Oxidative decarboxylation of cyclohexane monocarboxylic acid as a degenerate branching chain reaction II. Mechanism

Heberger,Keszler,Vidoczy,Gal,Cotarca,Delogu

, p. 1303 - 1307 (2007/10/02)

Based on the experimental results obtained studying the oxidative decarboxylation of cyclohexane monocarboxylic acid and published earlier, a mechanism is suggested, according to which in the thermal oxidation two main chain carrier radicals exist: tertiary and secondary peroxy radicals yielding cyclohexanone as well as hydroxy and keto acids in parallel reaction sequences. Carbon dioxide is formed in both pathways independently. The corresponding hydroperoxide molecules, formed during oxidation, decompose partly into radicals and partly into molecules resulting in degenerate branching and chemiluminescence phenomena, respectively. The rate determining termination is the cross combination process between secondary and tertiary peroxy radicals. The combinatorial generation of the mechanism of the thermal process and its reduction enabled the construction of the sequence network of the formation of products indicating that the primary attack of the hydrogen abstraction (secondary or tertiary) determines the product distribution.

Oxidative Decarboxylation of Cyclohexane Monocarboxylic Acid as a Degenerate Branching Chain Reaction. I. Kinetics

Nemes, I.,Heberger, K.,Keszler, A.,Vasvari, G.,Gal, D.,et al.

, p. 75 - 81 (2007/10/02)

Kinetics of product accumulation during the oxidative decarboxylation of cyclohexane monocarboxylic acid has been followed by GCMS, inhibitor and chemiluminescence methods.Results indicate that in the degenerate branching chain process selective (peroxy) radicals abstract predominantly tertiary hydrogen atoms from the substrate while non-selective (e.g. hydroxyl, alkoxy) radicals attack also secondary hydrogen atoms.The rate constant of the chain propagation was found to be kp = 7.5*106 exp (-57.6 kJ mol-1/RT) l mol-1 s-1.Furthermore it has been established, that the oxidative decarboxylation proceeds via two parallel pathways: one resulting in cyclohexanone, while the other avoiding the formation of the latter. Key Words: Chemical Kinetics / Elementary Reactions / Radicals / Oxidation, decarboxylation

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