435269-66-2

Upstream product

• 1669-43-8 (E)-4-isopropylbut-3-en-2-one 
• 98-80-6 phenylboronic acid 
• 28557-00-8 phenylzinc chloride 
• 876953-21-8 (E)-5-methyl-4-phenyl-3-hexen-2-one 
• 611-70-1 phenyl isopropyl ketone 
• 1225049-53-5 C₁₃H₁₆O 
• 1252192-76-9 C₁₉H₂₂O₃S 
• 914400-07-0 (E)-N-methoxy-N,4-dimethyl-3-phenylpent-2-enamide 
• 5166-53-0 5-methyl-3-hexene-2-one 
• 108-90-7 chlorobenzene 
• 17763-67-6 Phenyl triflate 
• 62751-30-8 (E)-ethyl 4-methyl-3-phenylpent-2-enoate 
• 1067206-24-9 dimethyl 5-methyl-2-oxo-4-phenylhexylphosphonate 
• 3262-89-3 triphenylboroxine 

Relevant academic research and scientific papers

Enantioselective Conjugate Addition of Aryl Halides and Triflates to Electron-Deficient Olefins via Nickel- And Rhodium-Catalyzed Sequential Relay Reactions

Asymmetric conjugate addition of aryl halides or aryl triflates to electron-deficient olefins was realized by sequential Miyaura borylation and Hayashi-Miyaura conjugate addition in one pot. A nickel-catalyzed borylation of aryl halides or triflates and a rhodium-chiral diene complex catalyzed enantioselective conjugate addition was executed as a pair of relay reactions as a more efficient and greener protocol.

Chiral porous organic frameworks for asymmetric heterogeneous catalysis and gas chromatographic separation

Three chiral robust diene-based porous organic frameworks (POFs) are prepared. POF-1 is shown to be an efficient heterogeneous catalyst after metallation for asymmetric conjugation addition with up to 93% ee, and it can also function as a new chiral stationary phase for gas chromatographic separation of racemates. This journal is

An N-linked bidentate phosphoramidite ligand (N-Me-BIPAM) for rhodium-catalyzed asymmetric 1,4-Addition of arylboronic acids to α,β-unsaturated ketones

A new bidentate phosphoramidite (N-Me-BIPAM) based on Shibasaki's N-linked BINOL was synthesized. This ligand appears to be highly effective for rhodium-catalyzed asymmetric conjugated addition of arylboronic acids to α,β-unsaturated enones. The reaction

(S)-Phenylalanine-derived chiral phosphorus-olefin ligands in rhodium-catalyzed asymmetric 1,4-addition reactions

Chiral phosphorus-olefins (S)-1, (S)-4, and (S)-5 have been designed and synthesized. These ligands were all synthesized from (S)-phenylalanine derivatives and act as phosphorus-olefin bidentate ligands to rhodium. The coordination face of the olefin can

Polymer-incarcerated chiral Rh/Ag nanoparticles for asymmetric 1,4-addition reactions of arylboronic acids to enones: Remarkable effects of bimetallic structure on activity and metal leaching

Robust and highly active bimetallic Rh nanoparticle (NP) catalysts, PI/CB Rh/Ag, have been developed and applied to the asymmetric 1,4-addition of arylboronic acids to enones without leaching of the metals. We found that the structures of the bimetallic Rh/Ag catalysts and chiral ligands strongly affect their catalytic activity and the amount of metal leaching. PI/CB Rh/Ag could be recycled several times by simple operations while keeping high yields and excellent enantioselectivities. To show the versatility of the PI/CB Rh/Ag catalyst, a one-pot, oxidation-asymmetric 1,4-addition reaction of an allyl alcohol and an arylboronic acid was demonstrated by combining the PI/CB Rh/Ag catalyst with PI/CB Au as an aerobic oxidation catalyst.

Highly enantioselective rhodium-catalyzed asymmetric 1,4-addition reactions of arylboronic acids to acyclic α,β-unsaturated compounds: The formal synthesis of (-)-indatraline

It's do or diene: Stable chiral bicyclo[2.2.1]diene ligands were synthesized from (-)-5-oxobornyl acetate and utilized in the asymmetric 1,4-addition reaction of arylboronic acids with acyclic α,β- unsaturated compounds. Low catalytic loading of the compl

Pd-catalyzed asymmetric hydrogenation of C=C bond of α,β- unsaturated ketones

Homogenous palladium-catalyzed asymmetric hydrogenation of C=C double bond of ,-unsaturated ketones has been -developed by using palladium(II) trifluoroacetate/(S)-7,7-bis-[di(4-methoxyphenyl]phosphino)-1,1-spirobiindane complex [Pd(OCOCF3)2-(S)-An-SDP] as the catalyst under ambient hydrogen pressure and room temperature with up to 89% ee. Georg Thieme Verlag Stuttgart · New York.

Enantioselective conjugate radical addition to α'-phenylsulfonyl enones

Enantioselective conjugate addition reactions of alkyl radicals to α'-phenylsulfonyl enones are described. A bis-oxazoline-zinc triflate complex proved to be an effective catalyst leading to high enantioselectivities and chemical yields.

Iron- and cobalt-catalyzed asymmetric hydrosilylation of ketones and enones with bis(oxazolinylphenyl)amine ligands

Chiral bis(oxazolinylphenyl)amines proved to be efficient auxiliary ligands for iron and cobalt catalysts with high activity for asymmetric hydrosilylation of ketones and asymmetric conjugate hydrosilylation of enones.

Highly active and enantioselective rhodium-catalyzed asymmetric 1,4-addition of arylboronic acid to α,β-unsaturated ketone by using electron-poor MeO-F12-BIPHEP

The asymmetric 1,4-addition of phenylboronic acid to cyclohexenone were performed by using a low amount of rhodium/(R)-(6,6′-dimethoxybiphenyl-2, 2′-diyl)bis[bis(3,4,5-trifluorophenyl)phosphine] (MeO-F 12-BIPHEP) catalyst. Because the catalyst