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Methyl 3beta-hydroxy-20-oxo-30-norlupan-28-oate is a naturally occurring triterpenoid compound, which belongs to the family of lupane-type triterpenoids. It is characterized by its unique chemical structure, featuring a 3-beta-hydroxyl group, a 20-oxo group, and a 30-norlupan-28-oate moiety. Methyl 3beta-hydroxy-20-oxo-30-norlupan-28-oate is derived from plants and has been found to possess various biological activities, such as anti-inflammatory, antitumor, and antimicrobial properties. Its chemical formula is C30H48O3, and it is a white crystalline solid with a molecular weight of 464.71 g/mol. Methyl 3beta-hydroxy-20-oxo-30-norlupan-28-oate has potential applications in the pharmaceutical and cosmetic industries due to its diverse therapeutic effects and relatively low toxicity.

4356-32-5

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4356-32-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4356-32-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,5 and 6 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4356-32:
(6*4)+(5*3)+(4*5)+(3*6)+(2*3)+(1*2)=85
85 % 10 = 5
So 4356-32-5 is a valid CAS Registry Number.

4356-32-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3β-Hydroxy-20-oxo-30-nor-lupansaeure-(28)-methylester

1.2 Other means of identification

Product number -
Other names (1R,3aS,5aR,5bR,9S,11aR,13aR)-1-Acetyl-9-hydroxy-5a,5b,8,8,11a-pentamethyl-icosahydro-cyclopenta[a]chrysene-3a-carboxylic acid methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4356-32-5 SDS

4356-32-5Downstream Products

4356-32-5Relevant academic research and scientific papers

Three lupane derivatives from Leptospermum scoparium

Mayer, Ralf

, p. 447 - 450 (1996)

The ether extract of the aerial parts of Leptospermum scoparium cultivars yielded a lactone with a 20,29,30-trinorlupane skeleton (1). Furthermore, 2α-hydroxyursolic acid (2), platanic acid (3) and 3β,30-dihydroxy-lup-20(29)-en-28-oic acid (4) were isolated.

Platanic acid: A new scaffold for the synthesis of cytotoxic agents

Kahnt, Michael,Heller, Lucie,Grabandt, Patricia,Al-Harrasi, Ahmed,Csuk, René

, p. 259 - 265 (2017/12/07)

Thirty-seven different derivatives (2-38) have been prepared from platanic acid, a natural occurring triterpenoid. Main emphasis was the introduction of several N-containing functional groups such as amines, amides and oximes and their screening for cytotoxic activity employing several human tumor cell lines using SRB assays. In these SRB assays, nearly all compounds showed good cytotoxicity for these human tumor cell lines. Two compounds (17 and 38), however, were submitted to extended biological testing and investigated with respect to their mode of action using fluorescence microscopy and FACS analysis. Compound 17, a methyl (3β 20R) 3-acetyloxy-20-amino-30-norlupan-28-oate, induced apoptosis in A2780 ovarian carcinoma cells.

COMPOUNDS FOR REDUCING GLUCOCORTICOIDS, AND METHODS OF TREATMENT THEREOF

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Paragraph 0181-0183, (2014/05/24)

A method for reducing glucocorticoids in an animal in need thereof comprising the use of compounds of the formula (I), wherein the definitions for R', R1-R11 and n are as disclosed in the description. The compounds of formula (I) are for the treatment or prevention of a glucocorticoid-related disorder for maintaining bone density, maintaining and improving the immune system, treating Cushing' s syndrome, treating obesity, improving reproduction efficiency, treating metabolic disorder, treating hypertension, treating hyperglycemia, treating insulin resistance, treating type 2 diabetes, and/or aiding in cancer and immune therapies

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