436089-66-6

Basic information

• Product Name: N-(3-AMINO-PHENYL)-4-FLUORO-BENZENESULFONAMIDE
• Synonyms: N-(3-AMINO-PHENYL)-4-FLUORO-BENZENESULFONAMIDE
• CAS NO: 436089-66-6
• Molecular Formula: C₁₂H₁₁FN₂O₂S
• Molecular Weight: 266.29
• Mol File: 436089-66-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 441.3 °C at 760 mmHg
• Flash Point: 220.7 °C
• Appearance: /
• Density: 1.439 g/cm³
• Vapor Pressure: 5.52E-08mmHg at 25°C
• Refractive Index: 1.652
• CAS DataBase Reference: N-(3-AMINO-PHENYL)-4-FLUORO-BENZENESULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-AMINO-PHENYL)-4-FLUORO-BENZENESULFONAMIDE(436089-66-6)
• EPA Substance Registry System: N-(3-AMINO-PHENYL)-4-FLUORO-BENZENESULFONAMIDE(436089-66-6)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 436089-66-6(Hazardous Substances Data)

Usage

Description

N-(3-AMINO-PHENYL)-4-FLUORO-BENZENESULFONAMIDE, also known as AF-219, is a chemical compound with potential pharmacological applications. It is a sulfonamide derivative with a fluorobenzene substitution and an amino-phenyl group. Its structure and properties make it a promising candidate for further research and development in the field of medicinal chemistry and drug discovery.

Uses

Used in Pharmaceutical Industry:
N-(3-AMINO-PHENYL)-4-FLUORO-BENZENESULFONAMIDE is used as a pharmaceutical agent for the treatment of various diseases and conditions. Its unique structure and properties make it a promising candidate for the development of new drugs and therapies.
Used in Medicinal Chemistry Research:
N-(3-AMINO-PHENYL)-4-FLUORO-BENZENESULFONAMIDE is used as a research compound in medicinal chemistry to study its potential applications and mechanisms of action. This can lead to the discovery of new drugs and therapeutic agents for various medical conditions.
Used in Drug Discovery:
N-(3-AMINO-PHENYL)-4-FLUORO-BENZENESULFONAMIDE is used in drug discovery efforts to identify and develop new pharmaceutical agents. Its unique structure and properties make it a valuable tool in the search for novel treatments and therapies.

InChI:InChI=1/C12H11FN2O2S/c13-9-4-6-12(7-5-9)18(16,17)15-11-3-1-2-10(14)8-11/h1-8,15H,14H2

Upstream product

• 1445792-33-5 C₁₇H₁₉FN₂O₄S 
• 349-88-2 4-Fluorobenzenesulfonyl chloride 
• 68621-88-5 (3-aminophenyl)carbamic acid tert-butyl ester 

Downstream Products

• 1445786-30-0 7-(2,4-dimethoxypyrimidin-5-yl)-4-((3-(4-fluorophenylsulfonamido)phenyl)amino)quinoline-3-carboxamide 

Relevant articles and documents

Sulfonamide urease inhibiting agent and preparation method and application thereof

Benzene sulfonamide compounds have a structural formula as shown in the specification, have great inhibiting effects on urease and can be used for preparation of medicines for treating gastritis, gastric ulcer, lithangiuria and the like. The invention fur