436095-50-0

Usage

Uses

Used in Pharmaceutical Research:
2-amino-N-propylbenzenesulfonamide is used as a research reagent for the preparation of pyrimidine derivatives. These derivatives have numerous pharmaceutical applications, making 2-amino-N-propylbenzenesulfonamide a valuable tool in the development of new drugs and therapies.
Used in Organic Synthesis:
In the field of organic chemistry, 2-amino-N-propylbenzenesulfonamide can be utilized as a building block or intermediate in the synthesis of more complex molecules. Its unique functional groups allow for a variety of reactions, making it a versatile compound for creating novel chemical entities with potential applications in various industries.
Used in Chemical Research:
As a research reagent, 2-amino-N-propylbenzenesulfonamide is also employed in chemical research to study the properties and reactivity of amino and sulfonamide groups. This can lead to a better understanding of the underlying chemistry and the development of new synthetic methods or applications for related compounds.

Upstream product

• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 89840-63-1 N-propyl-o-nitrobenzenesulfonamide 

Downstream Products

• 761440-02-2 2-(5-bromo-2-chloro-pyrimidin-4-ylamino)-N-propyl-benzenesulfonamide 
• 761440-00-0 2-(2-chloro-5-nitro-pyrimidin-4-ylamino)-N-methyl-benzenesulfonamide 
• 888969-40-2 2-[2-chloro-5-(2-ethoxy-vinyl)-pyrimidin-4-ylamino]-N-propyl-benzenesulfonamide 
• 888969-41-3 2-(2-chloro-pyrrolo[2,3-d]pyrimidin-7-yl)-N-propyl-benzenesulfonamide 

Relevant academic research and scientific papers

One-pot synthesis ofN-substituted benzannulated triazolesviastable arene diazonium salts

A mild and effective one-pot synthesis of 1,2,3-benzotriazin-4(3H)-ones and benzothiatriazine-1,1(2H)-dioxide analogues has been developed. The method involves the diazotisation and subsequent cyclisation of 2-aminobenzamides and 2-aminobenzenesulfonamidesviastable diazonium salts, prepared using a polymer-supported nitrite reagent andp-tosic acid. The transformation was compatible with a wide range of aryl functional groups and amide/sulfonamide-substituents and was used for the synthesis of pharmaceutically important targets. The synthetic utility of the one-pot diazotisaton-cyclisation process was further demonstrated with the preparation of an α-amino acid containing 1,2,3-benzotriazin-4(3H)-one.

Design and synthesis of 7H-pyrrolo[2,3-d]pyrimidines as focal adhesion kinase inhibitors. Part 2

A series of 2-amino-9-aryl-7H-pyrrolo[2,3-d]pyrimidines were designed and synthesized as focal adhesion kinase (FAK) inhibitors using molecular modeling in conjunction with a co-crystal structure. Chemistry was developed to introduce functionality onto th