761440-02-2Relevant articles and documents
Design and synthesis of 7H-pyrrolo[2,3-d]pyrimidines as focal adhesion kinase inhibitors. Part 2
Choi, Ha-Soon,Wang, Zhicheng,Richmond, Wendy,He, Xiaohui,Yang, Kunyong,Jiang, Tao,Karanewsky, Donald,Gu, Xiang-ju,Zhou, Vicki,Liu, Yi,Che, Jianwei,Lee, Christian C.,Caldwell, Jeremy,Kanazawa, Takanori,Umemura, Ichiro,Matsuura, Naoko,Ohmori, Osamu,Honda, Toshiyuki,Gray, Nathanael,He, Yun
, p. 2689 - 2692 (2007/10/03)
A series of 2-amino-9-aryl-7H-pyrrolo[2,3-d]pyrimidines were designed and synthesized as focal adhesion kinase (FAK) inhibitors using molecular modeling in conjunction with a co-crystal structure. Chemistry was developed to introduce functionality onto th
2, 4- DI (PHENYLAMINO) PYRIMIDINES USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES, INFLAMMATORY AND IMMUNE SYSTEM DISORDERS
-
Page 42, (2010/02/08)
Novel pyrimidine derivatives of formula (I), to processes for their production, their use as pharmaceuticals in the treatment of neoplastic diseases, inflammatory and immune system disorders and to pharmaceutical compositions comprising them.