436099-74-0Relevant academic research and scientific papers
Toward chelerythrine optimization: Analogues designed by molecular simplification exhibit selective growth inhibition in non-small-cell lung cancer cells
Yang, Rosania,Tavares, Maurício T.,Teixeira, Sarah F.,Azevedo, Ricardo A.,Pietro, Diego,Fernandes, Thais B.,Ferreira, Adilson K.,Trossini, Gustavo H.G.,Barbuto, José A.M.,Parise-Filho, Roberto
, p. 4600 - 4610 (2016)
A series of novel chelerythrine analogues was designed and synthesized. Antitumor activity was evaluated against A549, NCI-H1299, NCI-H292, and NCI-H460 non-small-cell lung cancer (NSCLC) cell lines in vitro. The selectivity of the most active analogues a
