436111-43-2Relevant academic research and scientific papers
1,5,7-Triazabicylodec-5-ene-promoted direct vinylogous aldol reaction for the synthesis of 3-hydroxy-2-oxoindole derivatives
Zhang, Xianhui,Zhou, Li,Mahmood, Qaiser,Zhao, Mengmeng,Wang, Xiaowu,Wang, Qinggang
, p. 573 - 576 (2019)
A simple and efficient method has been developed for the synthesis of 3-hydroxy-2-oxoindole derivatives through a direct vinylogous aldol reaction of allylic esters with isatins, catalyzed by 1,5,7-triazabicyclodec-5-ene. This method affords a variety of 3-hydroxy-2-oxoindole derivatives in moderate to excellent yields with high regioselectivities. An asymmetric version of this reaction catalyzed by Corey's chiral guanidine proceeded with moderate enantioselectivity. The protocol can also be used to synthesize isatin spiro ethers.
Palladium-catalyzed carboxylative coupling of benzyl chlorides with allyltributylstannane: Remarkable effect of palladium nanoparticles
Feng, Xiujuan,Sun, Anle,Zhang, Sheng,Yu, Xiaoqiang,Bao, Ming
supporting information, p. 108 - 111 (2013/04/10)
Palladium-catalyzed carboxylative coupling of benzyl chlorides with allyltributylstannane was successfully conducted to produce benzyl but-3-enoates in satisfactory to good yields. The carboxylative coupling reaction occurred smoothly under mild conditions in the presence of palladium nanoparticles in tetrahydrofuran.
