436153-70-7

Upstream product

• 69739-34-0 t-butyldimethylsiyl triflate 
• 632354-40-6 (2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-2-hydroxymethyltetrahydropyran-3-ol 
• 436153-84-3 (2R,3S,5R,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-2-hydroxymethyl-6-vinyl-tetrahydro-pyran-3-ol 
• 315203-85-1 (2R,4aR,6S,7R,8aS)-2-Phenyl-6-vinyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 100-39-0 benzyl bromide 
• 436153-69-4 tert-Butyl-dimethyl-((2R,4aR,6S,7R,8aS)-2-phenyl-6-vinyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yloxy)-silane 

Downstream Products

• 436153-85-4 ((2R,3R,5S,6R)-5-Benzyloxy-6-benzyloxymethyl-2-iodomethyl-tetrahydro-pyran-3-yloxy)-tert-butyl-dimethyl-silane 
• 436153-56-9 ((3R,5S,6R)-5-Benzyloxy-6-benzyloxymethyl-2-methylene-tetrahydro-pyran-3-yloxy)-tert-butyl-dimethyl-silane 
• 436153-89-8 (4aR,5aS,6aR,8S,9R,11aS,12aR,13aS)-8-(3-Hydroxy-propyl)-2-(4-methoxy-phenyl)-8-methyl-dodecahydro-1,3,5,7,12-pentaoxa-cyclohepta[b]anthracen-9-ol 
• 436153-91-2 (2R,3S,4aR,5aS,8R,9S,10aR,11aS)-8-Benzyloxy-9-(3-benzyloxy-propyl)-2,9-dimethyl-dodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalen-3-ol 
• 436153-75-2 [(2R,3S,4aR,5aS,8R,9S,10aR,11aS)-8-Benzyloxy-9-(3-benzyloxy-propyl)-2,9-dimethyl-dodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalen-3-yloxy]-tert-butyl-dimethyl-silane 
• 436153-50-3 Phosphoric acid (4aS,5aR,6aS,8R,9S,10aR,11aS,13aR)-9-(tert-butyl-dimethyl-silanyloxy)-4a,8-dimethyl-4a,5a,6,6a,8,9,10,10a,11a,12,13,13a-dodecahydro-4H-1,5,7,11-tetraoxa-benzo[4,5]cyclohepta[1,2-b]naphthalen-2-yl ester diphenyl ester 
• 850657-25-9 (2R,3S,4aR,5aS,8R,9S,10aR,11aS)-8-Benzyloxy-9-(3-benzyloxy-propyl)-3-(4-methoxy-benzyloxy)-2,9-dimethyl-dodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalene 
• 436153-48-9 (3S,4aR,5aS,8R,9S,10aR,11aS)-8-Benzyloxy-9-(3-benzyloxy-propyl)-3-(4-methoxy-benzyloxy)-9-methyl-2-methylene-dodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalene 
• 850656-60-9 (4aR,5aS,6aR,8S,9R,11aS,12aR,13aS)-9-Benzyloxy-8-(3-benzyloxy-propyl)-2-(4-methoxy-phenyl)-8-methyl-dodecahydro-1,3,5,7,12-pentaoxa-cyclohepta[b]anthracene 
• 436153-52-5 (2S,3S,4aR,5aS,8R,9S,10aR,11aS)-8-Benzyloxy-9-(3-benzyloxy-propyl)-2-iodomethyl-3-(4-methoxy-benzyloxy)-9-methyl-dodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalene 
• 436153-90-1 [(2R,3S,4aR,5aS,8R,9S,10aR,11aS)-8-Benzyloxy-9-(3-benzyloxy-propyl)-3-(4-methoxy-benzyloxy)-9-methyl-dodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalen-2-yl]-methanol 
• 436153-74-1 (2R,3S,4aR,5aS,8R,9S,10aR,11aS)-3,8-Bis-benzyloxy-2-benzyloxymethyl-9-(3-benzyloxy-propyl)-9-methyl-dodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalene 
• 436153-71-8 {(2S,3R,5S,6R)-5-Benzyloxy-2-[(6R,7S)-6-benzyloxy-7-(3-benzyloxy-propyl)-7-methyl-4,5,6,7-tetrahydro-oxepin-2-ylmethyl]-6-benzyloxymethyl-tetrahydro-pyran-3-yloxy}-tert-butyl-dimethyl-silane 
• 436153-87-6 (2S,6R,7S)-6-Benzyloxy-2-[(2S,3R,5S,6R)-5-benzyloxy-6-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-pyran-2-ylmethyl]-7-(3-benzyloxy-propyl)-7-methyl-oxepan-3-one 

Relevant academic research and scientific papers

Divergent synthesis of trans-fused polycyclic ethers by a convergent oxiranyl anion strategy

Octacyclic polyethers that correspond to the CDEFGHIJ-ring system of yessotoxin as well as G-and/or I-ring-modified analogues were synthesized in a divergent manner, starting from a common intermediate, using an [X + 2 + Y]-type convergent method. Reaction of a triflate with the oxiranyl anion generated from an epoxy sulfone, followed by ring expansion, allowed for the incorporation of medium-sized ring ethers into the key intermediate. Subsequent acetal formation and reductive etherification afforded various octacycles containing seven-and eight-membered ether rings.

Studies toward the total synthesis of gymnocin A, a cytotoxic polyether: A highly convergent entry to the F-N ring fragment

Matrix presented An efficient and highly convergent synthesis of the FGHIJKLMN ring fragment of gymnocin A, a cyctotoxic polycyclic ether isolated from the notorious red-tide forming dinoflagellate Gymnodinium mikimotoi, has been achieved. The present syn