4365-11-1 Usage
Uses
Used in Chemical Synthesis:
Benzenesulfonyl fluoride, 4-(1-methylethyl)-, is used as a connector in the assembly of -SO2linked small molecules with proteins or nucleic acids. This application is based on a new click chemistry approach through sulfates, which serves as a complimentary method to using amides and phosphate groups as linkers. The sulfonyl fluoride motif in Benzenesulfonyl fluoride, 4-(1-methylethyl)- allows for the formation of stable and reactive intermediates, facilitating the synthesis of various biologically active molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Benzenesulfonyl fluoride, 4-(1-methylethyl)-, can be utilized as a key intermediate in the development of novel drugs targeting various diseases. The unique structure of Benzenesulfonyl fluoride, 4-(1-methylethyl)- enables the formation of specific interactions with biological targets, potentially leading to the discovery of new therapeutic agents.
Used in Materials Science:
Benzenesulfonyl fluoride, 4-(1-methylethyl)-, may also find applications in materials science, particularly in the design and synthesis of advanced materials with tailored properties. Benzenesulfonyl fluoride, 4-(1-methylethyl)-'s ability to form -SO2linked small molecules can be exploited to create materials with enhanced stability, reactivity, or selectivity for specific applications.
Check Digit Verification of cas no
The CAS Registry Mumber 4365-11-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,6 and 5 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4365-11:
(6*4)+(5*3)+(4*6)+(3*5)+(2*1)+(1*1)=81
81 % 10 = 1
So 4365-11-1 is a valid CAS Registry Number.
4365-11-1Relevant academic research and scientific papers
SULFONATION OF CUMENE WITH SULFURIC AND HALOGENOSULFONIC ACIDS
Krylov, E.N.,Odintsova, G.N.
, p. 1695 - 1701 (2007/10/02)
The sulfonation of cumene by sulfuric and chloro- and fluorosulfonic acids in the range of 0-100 deg C under heterogenous and heterogenous-homogenous conditions gives mixtures of isomeric sulfonyl halides and/or sulfonic acids, in which the para isomer predominates (90-95percent of the total isomers at temperatures above 75 deg C and/or with the addition of the sulfonating agent to the cumene).If the reagents are mixed in the opposite order and at low temperatures (0-25 deg C), the proportion of the ortho isomer in the mixture of sulfo products increases to 20-22percent.The yield of the sulfonyl halides show an extremal relationship with temperature.The composition of the sulfonic acids and their halides formed under the conditions of a single experiment with the halogenosulfonic acids differ as a result, probably, of the nonequilibrium nature of the process and of the presence of several paths to the formation of the acid halides.
