4366-28-3

Upstream product

• 36881-00-2 2-(4-methoxyphenyl)-2-methyI-1,3-dioxolane 
• 107-21-1 ethylene glycol 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 

Downstream Products

• 114166-15-3 1-[2-(4-methoxy-phenyl)-[1,3]dioxolan-2-ylmethyl]-piperidine 
• 101108-45-6 diethyl-[2-(4-methoxy-phenyl)-[1,3]dioxolan-2-ylmethyl]-amine 
• 80336-89-6 2-Bromoethyl 2-(4-methoxyphenyl)acetate 
• 60233-15-0 1-((2-(4-methoxyphenyl)-1,3-dioxolane-2-yl)methyl)-1H-1,2,4-triazole 

Relevant academic research and scientific papers

Propiconazole-like compound, and preparation method and application thereof

The invention discloses a propiconazole-like compound, and a preparation method and application thereof. The structural formula of the propiconazole-like compound is represented by formula (I)shown in the specification. In the formula (I), X is H, bromine

LES TRIBROMURES DE PHOSPHONIUMS. AGENTS DE BROMINATION DE SUBSTRATS ORGANIQUES

The reactivities and selectivities of phosphonium tribromides 1-4 towards ketones and their ketals, in the presence of other functional group reactive toward bromide (free enolic position, activated aromatic ring or double bond), are studied and compared with the trimethyl phenyl ammonium tribromide 5.The abilities of the two kinds of tribromides are similar, with a better selectivity of phosphonium salts toward unsaturated ketones, which is probably induced by the greater stability of the ion-pair in phosphonium salts.They act essentially by the tribromide without specific bond interactions between phosphorus and heteroatom of the substrate.

A Lewis Acid Catalyzed 1,2 Aryl Shift in α-Haloalkyl Aryl Acetals: A Convenient Route to α-Arylalkanoic Acids

A new method for the synthesis of α-arylalkanoic acids is given, based on Lewis acid promoted rearrangement of acetals of primary and secondary α-haloalkyl aryl ketones (halo = Br, Cl) in hydrocarbon solvents.The reaction is selective, providing the esters of α-arylalkanoic acids in almost quantitative yields.The ability of "soft and borderline" Lewis acids in activating the carbon-halogen bond is compared with that of silver salts.The reaction mechanism is discussed.The present synthesis has been applied to some α-arylpropionic acids well-known as antiinflammatory drugs.