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2-bromoethyl (4-methoxyphenyl)acetate is an organic compound with the chemical formula C11H13BrO3. It is a colorless liquid at room temperature and is soluble in organic solvents. 2-bromoethyl (4-methoxyphenyl)acetate is characterized by the presence of a bromine atom attached to an ethyl group, which is connected to a phenyl ring with a methoxy group at the para position. The acetate group is attached to the other end of the ethyl chain. It is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals due to its unique structure and reactivity. The compound's properties, such as its bromine atom, make it a valuable building block for the creation of more complex molecules, particularly in the fields of drug development and chemical research.

80336-89-6

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80336-89-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 80336-89-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,3,3 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 80336-89:
(7*8)+(6*0)+(5*3)+(4*3)+(3*6)+(2*8)+(1*9)=126
126 % 10 = 6
So 80336-89-6 is a valid CAS Registry Number.

80336-89-6Downstream Products

80336-89-6Relevant academic research and scientific papers

A Lewis Acid Catalyzed 1,2 Aryl Shift in α-Haloalkyl Aryl Acetals: A Convenient Route to α-Arylalkanoic Acids

Castaldi, Graziano,Belli, Aldo,Uggeri, Fulvio,Giordano, Claudio

, p. 4658 - 4661 (2007/10/02)

A new method for the synthesis of α-arylalkanoic acids is given, based on Lewis acid promoted rearrangement of acetals of primary and secondary α-haloalkyl aryl ketones (halo = Br, Cl) in hydrocarbon solvents.The reaction is selective, providing the esters of α-arylalkanoic acids in almost quantitative yields.The ability of "soft and borderline" Lewis acids in activating the carbon-halogen bond is compared with that of silver salts.The reaction mechanism is discussed.The present synthesis has been applied to some α-arylpropionic acids well-known as antiinflammatory drugs.

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