437755-38-9

Upstream product

• 501-53-1 benzyl chloroformate 
• 2304-94-1 3-(benzyloxycarbonylamino)propanoic acid 
• 164223-35-2 ethyl 5-{[(benzyloxy)carbonyl]amino}-3-oxopentanoate 
• 437755-36-7 [2-(2-benzyloxycarbonylamino-ethyl)-[1,3]dioxolan-2-yl]-acetic acid 
• 437756-50-8 [2-(2-benzyloxycarbonylamino-ethyl)-[1,3]dioxolan-2-yl]-acetic acid ethyl ester 
• 437755-37-8 4-[2-(2-benzyloxycarbonylamino-ethyl)-[1,3]dioxolan-2-yl]-3-oxo-butyric acid ethyl ester 

Downstream Products

• 503601-22-7 ((S)-2-[2-(2-Benzyloxycarbonylamino-ethyl)-[1,3]dioxolan-2-yl]-1-{[methyl-(4-oxo-2-ureido-1,4,5,6-tetrahydro-pyrimidin-5-yl)-carbamoyl]-methyl}-ethyl)-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Dihydropyrimidinones--a new class of anti-staphylococcal antibiotics.

We report the synthesis and pharmacological evaluation of new derivatives of natural dipeptide antibiotic TAN-1057 A, B. In the course of this program, we identified novel analogues of the natural product that display similar antibacterial activity and showed improved tolerability.