164223-35-2

Basic information

• Product Name: ethyl 5-{[(benzyloxy)carbonyl]amino}-3-oxopentanoate
• Synonyms: ethyl 5-{[(benzyloxy)carbonyl]amino}-3-oxopentanoate
• CAS NO: 164223-35-2
• Molecular Weight: 293.32
• Mol File: 164223-35-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: ethyl 5-{[(benzyloxy)carbonyl]amino}-3-oxopentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-{[(benzyloxy)carbonyl]amino}-3-oxopentanoate(164223-35-2)
• EPA Substance Registry System: ethyl 5-{[(benzyloxy)carbonyl]amino}-3-oxopentanoate(164223-35-2)

Safety Data

• Hazardous Substances Data: 164223-35-2(Hazardous Substances Data)

Upstream product

• 2304-94-1 3-(benzyloxycarbonylamino)propanoic acid 
• 6148-64-7 ethyl potassium malonate 
• 1246303-67-2 [3-(2,2-dimethyl-4,6-dioxo-[1,3]dioxan-5-yl)-3-oxo-propyl]-carbamic acid benzyl ester 
• 1071-46-1 hydrogen ethyl malonate 
• 875932-90-4 (3-imidazol-1-yl-3-oxo-propyl)-carbamic acid benzyl ester 

Downstream Products

• 182247-94-5 ethyl (3R)-5-benzyloxycarbonylamino-3-hydroxypentanoate 
• 1454302-74-9 4-(2-amino-ethyl)-2-phenoxymethyl-oxazole-5-carboxylic acid ethyl ester 
• 1454302-81-8 5-(4-fluoro-phenyl)-2-phenoxymethyl-6,7-dihydro-5h-oxazolo [5,4-c]pyridin-4-one 
• 1454303-02-6 5-(5-fluoro-4-methoxy-pyrimidin-2-yl)-2-phenoxymethyl-6,7-dihydro-5H-oxazolo [5,4-c]pyridin-4-one 
• 1454303-09-3 2-phenoxymethyl-6,7-dihydro-5H-oxazolo[5,4-c]pyridin-4-one 
• 1454303-13-9 5-methyl-2-phenoxymethyl-6,7-dihydro-5H-oxazolo[5,4-c]pyridin-4-one 
• 1454302-65-8 5-benzyloxycarbonylamino-2-chloro-3-oxo-pentanoic acid ethyl ester 
• 1454302-66-9 5-benzyloxycarbonylamino-3-oxo-2-(2-phenoxy-acetoxy)-pentanoic acid ethyl ester 
• 1234064-19-7 Mini₁₀₆ 
• 164223-36-3 Ethyl 5-(2-benzyloxycarbonylaminoethyl)-3-methylisoxazole-4-carboxylate 
• 226704-28-5 5-(2-Benzyloxycarbonylaminoethyl)-3-methylisoxazole-4-carboxylic acid 
• 164223-48-7 3,5,7-Trimethyl-7-phenylseleno-4,5,6,7-tetrahydroisoxazolo<4,5-c>pyridin-4-one 
• 164223-47-6 3,5-Dimethyl-7-phenylseleno-4,5,6,7-tetrahydroisoxazolo<4,5-c>pyridin-4-one 
• 164223-41-0 3-Methyl-7-phenylseleno-4,5,6,7-tetrahydroisoxazolo<4,5-c>pyridin-4-one 

Relevant articles and documents

CONDENSED LACTAM DERIVATIVE

The present invention relates to a medicament for treating neuropsychiatric diseases, comprising a compound of Formula (1): or a pharmaceutically acceptable salt thereof, as an active ingredient.

3-‘4-HETEROCYCLYL -1,2,3,-TRIAZOL-1-YL!-N-ARYL-BENZAMIDES AS INHIBITORS OF THE CYTOKINES PRODUCTION FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES

Disclosed compounds of formula (I), which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

1,3-Dipolar cycloaddition route to nitrogen heterocyclic triones

1,3-Dipolar cycloaddition of nitrile oxides, formed in situ by dehydration of primary nitro compounds, with pyrrolidine enamines of protected γ- or δ-amino-β-keto esters affords isoxazole-4-carboxylates; these undergo lactam formation and N-O bond cleavage to afford 3-acyltetramic acids and 3-acyl-4-hydroxypyridin-2-ones.