437756-13-3

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 437756-10-0 2-amino-1-[4-(tert-butyl-dimethyl-silanyloxy)-benzooxazol-2-yl]-3-methyl-butan-1-ol 
• 437755-82-3 {(S)-1-[Hydroxy-(4-hydroxy-benzooxazol-2-yl)-methyl]-2-methyl-propyl}-carbamic acid benzyl ester 
• 437755-84-5 {1-[4-(tert-butyl-dimethyl-silanyloxy)-benzooxazole-2-carbonyl]-2-methyl-propyl}-carbamic acid benzyl ester 
• 437756-11-1 (S)-2-((S)-1-{[4-(tert-Butyl-dimethyl-silanyloxy)-benzooxazol-2-yl]-hydroxy-methyl}-2-methyl-propylcarbamoyl)-pyrrolidine-1-carboxylic acid benzyl ester 

Downstream Products

• 437756-15-5 [4-(2-{(S)-2-[(S)-1-(4-Hydroxy-benzooxazole-2-carbonyl)-2-methyl-propylcarbamoyl]-pyrrolidin-1-yl}-2-oxo-ethoxy)-phenoxy]-acetic acid tert-butyl ester 

Relevant academic research and scientific papers

Design and synthesis of peptide-based carboxylic acid-containing transition-state inhibitors of human neutrophil elastase.

In our search for a new agent, human neutrophil elastase (HNE) inhibitor, for the treatment of acute respiratory failure, we rationally designed and synthesized a series of peptide-based carboxylic acid-containing transition-state inhibitors. The presence