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Sodium 1-hydroxyethanesulphinate, also known as sodium 1-hydroxyethanesulfinate or sodium ethyl hydroxysulfinate, is a chemical compound with the formula C2H5NaO3S. It is a white crystalline solid that is soluble in water and is commonly used as a reducing agent in various chemical reactions. sodium 1-hydroxyethanesulphinate is particularly effective in the reduction of disulfides to thiols, a process that is crucial in the synthesis of certain pharmaceuticals and other organic compounds. It is also known for its ability to stabilize metal ions, which can be beneficial in preventing unwanted side reactions in chemical synthesis. Sodium 1-hydroxyethanesulphinate is a versatile reagent in organic chemistry, valued for its selectivity and mild reaction conditions.

4378-67-0

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4378-67-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4378-67-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,7 and 8 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4378-67:
(6*4)+(5*3)+(4*7)+(3*8)+(2*6)+(1*7)=110
110 % 10 = 0
So 4378-67-0 is a valid CAS Registry Number.
InChI:InChI=1/C2H6O3S.Na/c1-2(3)6(4)5;/h2-3H,1H3,(H,4,5);/q;+1/p-1

4378-67-0Downstream Products

4378-67-0Relevant academic research and scientific papers

Synthese d'α-Hydroxysulfinates

Mulliez, Michel,Naudy, Carole

, p. 2469 - 2476 (2007/10/02)

α-hydroxysulfinates 1 (table 1) are synthesized (path b, Fig. 1), by slowly adding aldehydes 3 to the mixture sodium dithionite 4 - sodium hydroxide.Owing to their limited stability the products 1 are readily separated from sodium sulfite 5 and isolated.They are easily distinguished (table 2) from their oxydation counterparts 2.

SYNTHESIS OF SODIUM HYDROXYETHYLSULFINATE AND INVESTIGATION OF ITS REACTIVITY.

Makarov,Budanov,Shalimova

, p. 1004 - 1007 (2007/10/02)

The authors examine details of the preparation, and data on the reactivity of sodium hydroxyethylsulfinate (HES). As the result of studies of the dependence of the yield on concentration and temperature, and investigations of various methods of purification of the end product, the authors found the synthesis conditions for obtaining HES in fairly high yield (80%) and of at least 90% purity. Based on experimental data, it is shown that the mechanism of reducing action of various hydroxyalkysulfinates consists of successive stages of decomposition of the reducing agents with formation of HSO//2** minus or H//2SO//2 , and interaction of the latter with the dyes.

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