4379-13-9

Basic information

• Product Name: L-ISOLEUCINOL HYDROCHLORIDE
• Synonyms: 2-azanyl-3-methyl-pentan-1-ol;2-amino-3-methylpentan-1-ol(SALTDATA: FREE)
• CAS NO: 4379-13-9
• Molecular Formula: C₆H₁₅NO
• Molecular Weight: 117.1894
• Mol File: 4379-13-9.mol

Chemical Properties

• Boiling Point: 196.9°Cat760mmHg
• Flash Point: 100.6°C
• Appearance: /
• Density: 0.904g/cm³
• Storage Temp.: −20°C
• PKA: 12.88±0.10(Predicted)
• CAS DataBase Reference: L-ISOLEUCINOL HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: L-ISOLEUCINOL HYDROCHLORIDE(4379-13-9)
• EPA Substance Registry System: L-ISOLEUCINOL HYDROCHLORIDE(4379-13-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 4379-13-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Production:
L-Isoleucinol hydrochloride is used as an active pharmaceutical ingredient for the development of various medications, leveraging its inherent properties to enhance therapeutic effects.
Used in Organic Synthesis:
L-Isoleucinol hydrochloride is utilized as a key intermediate in the synthesis of a range of organic compounds, contributing to the creation of diverse chemical products.
Used in Antimicrobial Agents Development:
L-Isoleucinol hydrochloride is employed as an antimicrobial agent due to its demonstrated antibacterial and antifungal properties, offering a potential solution for combating microbial infections.
Used as a Chiral Building Block:
In the preparation of chiral drugs and pharmaceuticals, L-Isoleucinol hydrochloride is used as a chiral building block, essential for the synthesis of enantiomerically pure compounds, which is crucial for ensuring the desired biological activity and reducing potential side effects.
Used in Different Industries:
Depending on the specific requirements of various industries, L-Isoleucinol hydrochloride may find application in areas such as agriculture for its antimicrobial properties in crop protection, or in the chemical industry for the synthesis of specialty chemicals and materials.

InChI:InChI=1/C6H15NO/c1-3-5(2)6(7)4-8/h5-6,8H,3-4,7H2,1-2H3

Upstream product

• 73-32-5 L-isoleucine 
• 73-32-5 DL-isoleucine 

Downstream Products

• 635291-29-1 3-Nitro-4-chloro-N-[(1S,2 S)-1-(hydroxymethyl)-2-methylbutyl]benzenesulfonamide 
• 1422518-32-8 2-(1-methylpropyl)-5-phenyl-1H-pyrrole 
• 635291-27-9 4-Iodo-N-[(1S,2S)-1-(hydroxymethyl)-2-methylbutyl]benzenesulfonamide 
• 152338-16-4 4-chloro-N-[(1S,2S)-1-(hydroxymethyl)-2-methylbutyl]-benzenesulfonamide 

Relevant articles and documents

Asymmetric Synthesis Using Chirally Modified Borohydrides. Part 1. Enantioselective Reduction of Aromatic Ketones with the Reagent Prepared from Borane and (S)-Valinol

The asymmetric reduction of aromatic ketones with the reagents prepared from borane and chiral aminoalcohols was studied under various conditions.The ratio of borane to (S)-valinol was found to be optimum at 2-3:1, when up to 65-73percent selectivity was obtained in the reduction of n-propyl phenyl ketone.The amino-alkoxy-amine-boranes (2) and/or (3) were tentatively proposed as the reaction species responsible for asymmetric induction.