4379-29-7Relevant academic research and scientific papers
Some unusual reactions of Meldrum's acid. Synthesis of cinnamic acids, coumarins and 2-benzyl-1-indanone
Mahulikar,Mane
, p. 12 - 14 (2007/10/03)
The use of Meldrum's acid (1) in the synthesis of the substituted cinnamic acid 3 and malonic acid 4, the coumarins 8 and 9, and of 2-benzyl-1-indanone (13), is reported. The structure of benzylidene benzalmalonate is corrected to 14.
Synthesis of 5-alkylidene-1,3-dioxane-4,6-diones, an easily accessible family of axially chiral alkenes: Preparation in non-racemic form and platinum binding studies
Casadesus, Meritxell,Coogan, Michael P.,Ooi, Li-Ling
, p. 3822 - 3830 (2008/09/18)
A general synthetic route to 5-alkylidene-1,3-dioxane-4,6-diones, which are a family of axially chiral alkenes, is described. Conformational issues are explored and the platinum-binding properties of these species are discussed. That these alkenes exist as stable enantiomers is established by their partial kinetic resolution upon reaction with cysteine. The Royal Society of Chemistry 2006.
