438192-84-8

Upstream product

• 32147-20-9 (Z)-2-bromo-1,3-diphenylprop-2-en-1-one 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 611-91-6 2,3-dibromo-1,3-diphenylpropane-1-one 
• 558-13-4 carbon tetrabromide 
• 100-52-7 benzaldehyde 

Downstream Products

• 405933-13-3 (Z)-2-bromo-1,3-diphenylprop-2-en-1-yl acetate 
• 1254219-16-3 C₂₅H₂₄BrNO₂S 
• 3780-00-5 1-(3-phenyl-1,2-propadienyl)benzene 
• 405933-15-5 (Z)-2-bromo-1,3-diphenylprop-2-en-1-yl 2,2,2-trichloroacetate 

Relevant academic research and scientific papers

Efficient ring-closing metathesis of alkenyl bromides: The importance of protecting the catalyst during the olefin approach

We present the first productive ring-closing metathesis reaction that leads to the construction of cyclic alkenyl bromides. Efficient catalysis employing commercially available Grubbs II catalyst is possible through appropriate modification of the starting bromoalkene moiety.

Synthesis of allenes from allylic alcohol derivatives bearing a bromine atom using a palladium(0)/diethylzinc system

A general and efficient synthesis of allenes using a palladium(0)/diethylzinc system is described. Treatment of mesylates or trichloroacetates of (E)- or (Z)-2-bromoalk-2-en-1-ols with diethylzinc in the presence of a catalytic amount of palladium(0) affords allenes bearing an aminoalkyl, alkyl, or aryl substituent(s) in good to high yields. No transfer of chirality from the stereogenic center carrying the mesyloxy group to the allene was observed.

Three-component synthesis of 2-haloalk-2(Z)-en-1-ols via tandem haloalkylidenation-aldehyde addition

Cr(II)-induced condensation of CCl4 or CBr4 with an aldehyde stereospecifically generates an (E)-α-haloalkylidene chromium carbenoid which adds in situ to a second equivalent of aldehyde furnishing 2-haloalk-2(Z)-en-1-ols in high yie