438206-68-9

Upstream product

• 86803-29-4 4-ethenyl-1-(triphenylmethyl)-1H-imidazole 
• 680186-47-4 (1-trityl-1H-imidazol-4-yl)-propynoic acid ethyl ester 
• 680186-40-7 3-(1-trityl-1H-imidazol-4-yl)-prop-2-yn-1-ol 
• 680186-43-0 (Z)-4-(2-bromo-1-fluoroethenyl)-1-trityl-1H-imidazole 
• 680186-41-8 4-(1,2-dibromoethyl)-1-trityl-1H-imidazole 
• 680186-38-3 4-(ethynyl)-1-trityl-1H-imidazole 
• 33016-47-6 (1-tritylimidazol-4-yl)carboxaldehyde 
• 438206-64-5 methyl (Z)-1-trityl-urocanate 
• 680186-45-2 (E)-2-bromo-3-fluoro-3-(1-trityl-1H-imidazol-4-yl)prop-2-en-1-ol 

Downstream Products

• 438206-70-3 (Z)-3-fluoro-3-(1-trityl-1H-imidazol-4-yl)acrylic acid 
• 438206-69-0 (Z)-3-fluoro-3-(1-trityl-1H-imidazol-4-yl)prop-2-enal 

Relevant academic research and scientific papers

New approaches to side-chain fluorinated bioimidazoles: 4-alkynylimidazoles as substrates for fluorination

4-Alkynylimidazoles have been prepared and their behavior as substrates for "FBr" addition (NBS+Et3N·3HF) have been studied. Facile Markownikov addition to ethylnylimidazole 2 gave fluorobromoolefin 9a, a potential synthon for the 2-imidazolyl-

New building blocks for fluorinated bioimidazole derivatives II: Preparation of β-fluorourocanic acids

Replacement of vinyl hydrogen with fluorine is based on addition of an FBr equivalent to a double bond followed by HBr elimination. This sequence has been adapted to prepare 3-fluoro-3-imidazolylpropenoic acids (β-fluorourocanic acids), and the related fl