438231-80-2

Upstream product

• 62-53-3 aniline 
• 136678-70-1 4-phenyl-6-methyl-3,4-dihydro-2-pyranone 
• 6049-47-4 5-oxo-3-phenylhexanoic acid 
• 1261085-76-0 5-acetyl-6-methyl-4-phenyl-3,4-dihydro-2H-pyran-2-one 
• 104-55-2 3-phenyl-propenal 
• 4354-90-9 (3-oxo-1-phenyl-butyl)-malonic acid 

Relevant academic research and scientific papers

DBU-Catalyzed Ring-Opening and Retro-Claisen Fragmentation of Dihydropyranones

We present a general protocol for the formal Michael addition of acetone to α,β-unsaturated esters and amides, a transformation difficult to perform using current methods. The protocol comprises of an amidine catalyzed relay ring-opening and fragmentation