438497-31-5

Basic information

• Product Name: di-[2-methoxy-6-[(1S)-1-(methylthio)ethyl]phenyl]diselenide
• Synonyms: di-[2-methoxy-6-[(1S)-1-(methylthio)ethyl]phenyl]diselenide
• CAS NO: 438497-31-5
• Molecular Weight: 520.477
• Mol File: 438497-31-5.mol

Chemical Properties

• CAS DataBase Reference: di-[2-methoxy-6-[(1S)-1-(methylthio)ethyl]phenyl]diselenide(CAS DataBase Reference)
• NIST Chemistry Reference: di-[2-methoxy-6-[(1S)-1-(methylthio)ethyl]phenyl]diselenide(438497-31-5)
• EPA Substance Registry System: di-[2-methoxy-6-[(1S)-1-(methylthio)ethyl]phenyl]diselenide(438497-31-5)

Safety Data

• Hazardous Substances Data: 438497-31-5(Hazardous Substances Data)

Upstream product

• 438497-32-6 1-methoxy-3-[(1S)-1-(methylthio)ethyl]benzene 
• 586-37-8 1-(3-Methoxyphenyl)ethanone 
• 23308-82-9 (R)-(+)-1-(3-methoxyphenyl)-1-ethanol 

Downstream Products

• 819852-45-4 C₁₀H₁₃BrOSSe 
• 438497-34-8 1-methoxy-2-[(1S,2R)-2-methoxy-1-methyl-2-phenylethyl]seleno-3-[(1S)-1-(methylthio)ethyl]benzene 
• 438497-41-7 (1R,2S)-2-({2-methoxy-6-[(1S)-1-(methylthio)ethyl]phenyl}seleno)-1-phenylpropan-1-ol 
• 442554-30-5 2-[({2-methoxy-6-[(1S)-1-(methylthio)ethyl]phenyl}seleno)methyl]-5-methyl-3,4-dihydro-2H-pyrrole 1-oxide 
• 606965-25-7 N-{(1R,2S)-1-Butyl-2-[2-methoxy-6-((S)-1-methylsulfanyl-ethyl)-phenylselanyl]-hexyl}-benzamide 
• 606965-24-6 N-{(1R,2S)-1-Butyl-2-[2-methoxy-6-((S)-1-methylsulfanyl-ethyl)-phenylselanyl]-hexyl}-acetamide 
• 606965-20-2 2-((1S,2R)-2-Azido-1-butyl-hexylselanyl)-1-methoxy-3-((S)-1-methylsulfanyl-ethyl)-benzene 

Relevant articles and documents

Preparation of a new chiral non-racemic sulfur-containing diselenide and applications in asymmetric synthesis

The synthesis of the new chiral non-racemic sulfur-containing diselenide, di-2-methoxy-6-[(1S)-1-(methylthio)ethyl]phenyl diselenide, is described. When treated with ammonium persulfate this diselenide is transformed into the corresponding selenenyl sulfate, which acts as a strong electrophilic reagent and adds to alkenes, in the presence of methanol or water, to afford the products of selenomethoxylation or selenohydroxylation, respectively, with excellent diastereoselectivities. Starting from alkenes containing internal nucleophiles, asymmetric cyclofunctionalization reactions also resulted in good chemical yields, complete regioselectivities, and high diastereoselectivities. This sulfur-containing diselenide can also be used in catalytic amounts to promote one-pot selenenylation-deselenenylation processes, from which several types of products can be obtained in high yield and with good enantiomeric excess.