438526-42-2

Upstream product

• 89-56-5 5-Methylsalicylic acid 
• 3282-30-2 pivaloyl chloride 

Downstream Products

• 438526-47-7 2,2-dimethyl-propionic acid 4-[((carboxy)-(3-chloro-4,5-dihydro-isoxazol-5-yl)-methyl)carbamoyloxymethyl]-2-[(2-(3-carboxymethylsulfanyl-2,5-dioxo-pyrrolidin-1-yl)-ethyl)carbamoyl]-phenyl ester 
• 438526-46-6 2,2-dimethyl-propionic acid 4-[((carboxy)-(3-chloro-4,5-dihydro-isoxazol-5-yl)-methyl)carbamoyloxymethyl]-2-[(2-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-ethyl)carbamoyl]-phenyl ester 
• 438526-45-5 2,2-dimethyl-propionic acid 2-[(2-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-ethyl)carbamoyl]-4-(4-nitro-phenoxycarbonyloxymethyl)-phenyl ester 
• 438526-44-4 2,2-dimethyl-propionic acid 2-[(2-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-ethyl)carbamoyl]-4-hydroxymethyl-phenyl ester 
• 438526-43-3 2-(2,2-dimethyl-propionyloxy)-5-hydroxymethyl-benzoic acid 

Relevant academic research and scientific papers

A new acivicin prodrug designed for tumor-targeted delivery

Acivicin is an antitumor agent known to inhibit cell growth. A new prodrug 9b of acivicin 10 was synthesized, based on a p-hydroxybenzylcarbamate self-immolative spacer capable to release acivicin under esterase activity. The prodrug includes a maleimide-