438634-98-1

Basic information

• Product Name: 6-Benzothiazolecarboxaldehyde,2,3-dihydro-2-oxo-(9CI)
• Synonyms: 6-Benzothiazolecarboxaldehyde,2,3-dihydro-2-oxo-(9CI);2-oxo-2,3-dihydrobenzo[d]thiazole-6-carbaldehyde;6-Benzothiazolecarboxaldehyde, 2,3-dihydro-2-oxo-
• CAS NO: 438634-98-1
• Molecular Formula: C8H5NO2S
• Molecular Weight: 179.1958
• Product Categories: BENZOTHIAZOLE
• Mol File: 438634-98-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-Benzothiazolecarboxaldehyde,2,3-dihydro-2-oxo-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Benzothiazolecarboxaldehyde,2,3-dihydro-2-oxo-(9CI)(438634-98-1)
• EPA Substance Registry System: 6-Benzothiazolecarboxaldehyde,2,3-dihydro-2-oxo-(9CI)(438634-98-1)

Safety Data

• Hazardous Substances Data: 438634-98-1(Hazardous Substances Data)

Upstream product

• 62266-82-4 6-bromo-1,3-benzothiazol-2(3H)-one 
• 75-16-1 methylmagnesium bromide 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1435516-81-6 trans-4-[[3-(6-formyl-2-oxo-1,3-benzothiazol-3(2H)-yl)propyl](methyl)amino]cyclohexyl hydroxy(di-2-thienyl)acetate 

Relevant articles and documents

BENZO RING DERIVATIVE WITH B2 RECEPTOR AGONIST AND M3 RECEPTOR ANTAGONIST ACTIVITIES AND USE THEREOF IN MEDICINE

A compound represented by general formula (I), or a stereoisomer, a hydrate, a metabolite, a solvate, a pharmaceutically acceptable salt, a cocrystal, or a prodrug thereof, the preparation method thereof, and use thereof in the manufacture of a medicament for treatment of an airway obstructive disease, wherein the substituents are defined as in the specification.

A Simple strategy for the preparation of 6-substituted 3H-benzoxazol-2-ones and 3H-benzothiazol-2-ones

The double metallation of 6-bromo-3H-benzothiazol-2-one and 6-bromo-3H-benzoxazol-2-one with methyl magnesium bromide and alkyllithium bases is described. Alkylation with a variety of electrophiles occurs at the 6-position of the heterocycles in good yiel