4389-05-3Relevant articles and documents
Synthesis of novel sulfonamides under mild conditions with effective inhibitory activity against the carbonic anhydrase isoforms I and II
Ba?ar, Erhan,Tunca, Ekrem,Bülbül, Metin,Kaya, Muharrem
, p. 1356 - 1361 (2016)
Novel sulfonamide derivatives 6a–i, as new carbonic anhydrase inhibitors which candidate for glaucoma treatment, were synthesized from the reactions of 4-amino-N-(4-sulfamoylphenyl) benzamide 4 and sulfonyl chloride derivatives 5a–i with high yield (71–90
Microwave assisted synthesis of novel tetrazole/sulfonamide derivatives based on octahydroacridine, xanthene and chromene skeletons as inhibitors of the carbonic anhydrases isoforms I, II, IV and VII
Esirden, ?brahim,Tan?, Muhammet,Supuran, Claudiu T.,Kaya, Muharrem
, p. 86 - 89 (2016/12/09)
The synthesis of novel tetrazole/sulfonamide derivatives based on octahydroacridine, xanthene and chromene scaffold by using microwave (MW) assisted techniques is reported in this study. These synthesized hybrid compounds were assayed for the inhibition o
Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII
Eldehna, Wagdy M.,Fares, Mohamed,Ceruso, Mariangela,Ghabbour, Hazem A.,Abou-Seri, Sahar M.,Abdel-Aziz, Hatem A.,Abou El Ella, Dalal A.,Supuran, Claudiu T.
, p. 259 - 266 (2016/07/06)
By using a molecular hybridization approach, two series of amido/ureidosubstituted benzenesulfonamides incorporating substituted-isatin moieties were synthesized. The prepared derivatives were in vitro evaluated for their inhibitory activity against human
Synthesis of novel acridine and bis acridine sulfonamides with effective inhibitory activity against the cytosolic carbonic anhydrase isoforms II and VII
Ulus, Ramazan,Yesildag, Ibrahim,Tanc, Muhammet,Buelbuel, Metin,Kaya, Muharrem,Supuran, Claudiu T.
, p. 5799 - 5805 (2013/09/12)
4-Amino-N-(4-sulfamoylphenyl)benzamide was synthesized by reduction of 4-nitro-N-(4-sulfamoylphenyl)benzamide and used to synthesize novel acridine sulfonamide compounds, by a coupling reaction with cyclic-1,3-diketones and aromatic aldehydes. The new com