4390-52-7

Basic information

• Product Name: N-phenyl-N-[1-phenyl-1-(pyrid-2-yl)]methylamine
• Synonyms: N-phenyl-N-[1-phenyl-1-(pyrid-2-yl)]methylamine
• CAS NO: 4390-52-7
• Molecular Weight: 260.338
• Mol File: 4390-52-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: N-phenyl-N-[1-phenyl-1-(pyrid-2-yl)]methylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl-N-[1-phenyl-1-(pyrid-2-yl)]methylamine(4390-52-7)
• EPA Substance Registry System: N-phenyl-N-[1-phenyl-1-(pyrid-2-yl)]methylamine(4390-52-7)

Safety Data

• Hazardous Substances Data: 4390-52-7(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 832-81-5 3-phenyl-[1,2,3]triazolo[1,5-a]pyridine 
• 30894-24-7 N-(phenyl(pyridin-2-yl)methylene)aniline 
• 91-02-1 phenyl(pyridin-2-yl)methanone 
• 30894-24-7 N-(phenyl(pyridin-2-yl)methylene)aniline 
• 109-09-1 2-chloropyridine 
• 538-51-2 benzylidene phenylamine 
• 110-86-1 pyridine 
• 5029-67-4 2-iodopyridine 

Relevant articles and documents

TBAB-Catalyzed Csp3–N Bond Formation by Coupling Pyridotriazoles with Anilines: A New Route to (2-Pyridyl)alkylamines

A new metal-free procedure allowing Csp3–N bond formation through coupling of pyridotriazoles and weakly nucleophilic anilines has been developed. This sustainable reaction shows high tolerance towards functional groups (ketones, free alcohols) leading to 2-picolylamine derivatives. The key to our success is the use of a catalytic amount of TBAB and water as a co-solvent leading to the formation of pyridylalkylamine derivatives. As this coupling tolerates the presence of Csp2–Br bond on both partners of the reaction, we performed a sequential one-pot reaction between functionalized triazolopyridines and anilines followed by a second coupling with N-tosylhydrazones leading to the formation of Csp3–N and Csp2–Csp2 bonds.

Light-induced metal-free transformations of unactivated pyridotriazoles

A highly efficient and practical method for incorporation of the arylmethylpyridyl moiety into diverse molecules has been developed. This method features the transition metal-free light-induced room temperature transformation of pyridotriazoles into pyridyl carbenes, which are capable of smooth arylation, X-H insertion, and cyclopropanation reactions. The synthetic usefulness of the developed method was illustrated in a facile synthesis of biologically active molecules.

Correction to: Photocatalytic and Chemoselective Transfer Hydrogenation of Diarylimines in Batch and Continuous Flow (Organic Letters (2018) 20:4 (905-908) DOI: 10.1021/acs.orglett.7b03565)

Sections of Schemes 2 and 4 were omitted in error during the production process. The complete versions of Schemes 2 and 4 are shown below.(Figure Persented).Scheme 2 is corrected as follows:.