439120-99-7

Basic information

• Product Name: 1-(TERT-BUTYL)-4-[(4-METHYLPHENYL)SULFONYL]-1,3-DIHYDRO-2H-IMIDAZOL-2-ONE
• Synonyms: 1-(TERT-BUTYL)-4-[(4-METHYLPHENYL)SULFONYL]-1,3-DIHYDRO-2H-IMIDAZOL-2-ONE;1-tert-butyl-4-(4-methylbenzenesulfonyl)-2,3-dihydro-1H-imidazol-2-one
• CAS NO: 439120-99-7
• Molecular Formula: C14H18N2O3S
• Molecular Weight: 294.37
• Mol File: 439120-99-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(TERT-BUTYL)-4-[(4-METHYLPHENYL)SULFONYL]-1,3-DIHYDRO-2H-IMIDAZOL-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(TERT-BUTYL)-4-[(4-METHYLPHENYL)SULFONYL]-1,3-DIHYDRO-2H-IMIDAZOL-2-ONE(439120-99-7)
• EPA Substance Registry System: 1-(TERT-BUTYL)-4-[(4-METHYLPHENYL)SULFONYL]-1,3-DIHYDRO-2H-IMIDAZOL-2-ONE(439120-99-7)

Safety Data

• Hazardous Substances Data: 439120-99-7(Hazardous Substances Data)

Upstream product

• 824-79-3 sodium 4-methylbenzenesulfinate 
• 1118-12-3 1,1-dimethylethylurea 
• 536-57-2 p-toluene sulfinic acid 
• 131543-46-9 Glyoxal 
• 1609-86-5 Tert-butyl isocyanate 

Relevant articles and documents

Solid-phase synthesis of disubstituted 1,3-dihydro-2H-imidazol-2-ones

An efficient and straightforward solid-phase synthesis of sulfonylimidazolones 2a-g is described. Our design was directed toward obtaining molecules for a general library development and incorporates functionalities that fulfill lead-like criteria. The synthesis was realized with the use of SPOS in fair to good yields and purity. Monitoring and quantitation of intermediates and final products were performed by the use of LCMS and NMR spectroscopy.

Generality and scope of the synthesis of 2-arylpyrrolo[3,4-b] quinoxaline-1,3-diones from 2,3-dichloro-N-arylmaleimides. II

Nucleophilic substitution of 2,3-dichloro-N-arylmaleimides (1) and (2) with a series of arylamines gives 2-arylamino-3-chloro-N-arylmaleimides (3) and (4), respectively. When 4 is treated with sodium azide at room temperature, it cyclizes to the 2-(p-methoxyphenyl)pyrrolo[3,4-b]quinoxaline- 1,3-diones (5). Under the same conditions, the 2-(p-nitrophenyl) analogue (3) fails to cyclize. Ring closure is also subject to the steric and electronic effects of substituents in the nucleophile.