4392-27-2Relevant academic research and scientific papers
FUNCTIONAL GROUP MODIFICATION VIA ORGANOTELLURIUM CHEMISTRY. SYNTHESIS OF ALLYL ALCOHOLS FROM CHLOROMETHYLOXIRANES.
Polson, George,Dittmer, Donald C.
, p. 5579 - 5582 (1986)
Treatment of 2-substitued-2-chloromethyloxiranes with telluride ion gives 2-substitued allyl alcohols, presumably through an epitelluride intermediate.
Catalytic epoxidation of alkenes with 30% H2O2 over Mn2+-exchanged zeolites
Qi,Lu,Zhou,Xia,Tang,Fang,Pang,Dong
experimental part, p. 73 - 79 (2010/07/09)
The Mn2+-exchanged zeolites Mn-Y, Mn-beta, Mn-A and Mn-ZSM-5 were prepared and used as heterogeneous catalysts for the liquid phase epoxidation of alkenes with aqueous hydrogen peroxide (30% H2O2) at 273-298 K in the NaHCO3 buffer system. The structures of catalysts were characterized by powder X-ray diffraction (XRD), UV-vis, ICP, BET and IR techniques. Mn-beta and Mn-Y exhibited the best recyclable activity for the epoxidation of styrene to achieve styrene conversions higher than 96.0 and 98.5 mol%, respectively. Mn-beta showed higher activity for cyclohexene and norbornene but lower activity for α-methylstyrene, cinnamyl chloride, indene, cyclooctene and α-pinene than Mn-Y, which could be correlated with the difference of their pore sizes. However, these catalysts did not show any activity for the epoxidation of 1-octene with H2O2, possibly due to low electron density of double bonds of linear terminal alkenes.
Cyclic benzamidines as orally efficacious NR2B-selective NMDA receptor antagonists
Nguyen, Kevin T.,Claiborne, Christopher F.,McCauley, John A.,Libby, Brian E.,Claremon, David A.,Bednar, Rodney A.,Mosser, Scott D.,Gaul, Stanley L.,Connolly, Thomas M.,Condra, Cindra L.,Bednar, Bohumil,Stump, Gary L.,Lynch, Joseph J.,Koblan, Kenneth S.,Liverton, Nigel J.
, p. 3997 - 4000 (2008/02/10)
A novel series of cyclic benzamidines was synthesized and shown to exhibit NR2B-subtype selective NMDA antagonist activity. Compound 29 is orally active in a carrageenan-induced rat hyperalgesia model of pain.
Convenient method for epoxidation of alkenes using aqueous hydrogen peroxide
Man, Kin Tse,Klawonn, Markus,Bhor, Santosh,Doebler, Christian,Anilkumar, Gopinathan,Hugl, Herbert,Maegerlein, Wolfgang,Beller, Matthias
, p. 987 - 990 (2007/10/03)
(Chemical Equation Presented) The complex [Ru(tpy)(pydic)] (1a) is an active catalyst for epoxidation of alkenes by aqueous 30% hydrogen peroxide in tertiary alcohols. The protocol is simple to operate and gives the corresponding epoxides in good to excellent yields. Chiral enantiopure [Ru(tpy*)(pydic) ] complexes have been synthesized and successfully applied in this procedure.
